Effectiveness of continuous glucose monitoring in children, adolescents, and young adults with poorly controlled type 1 diabetes
Objective—The purpose of this study was to determine the effect of continuous glucose monitoring (CGM) on glycemic control in children, adolescents, and young adults ages 7–21 years with poorly controlled diabetes HbA1c 9.0% or more (74 mmol/mol IFCC). Materials and Methods—The primary outcome was improvement in HbA1c. The secondary outcome included self-reported hypoglycemia. This 12-week study used a prospective, one-group, pre- and posttest pre-experimental design with a convenience sample. The study used the Medtronic Guardian CGM with Enlite Sensor. Results and Conclusions—Thirty-three subjects enrolled in the study. The mean age of the participants was 15.57 years, range was 11–20 years, 47.6% were male, and 52.4% were female. Twenty-one (63.6%) completed the final study visit. There was a clinically and statistically significant reduction of 1.46 (SD = 1.6711) (p = .001) in HbA1c at 12 weeks. Fifteen of the 21 participants (71.4%) had an HbA1c reduction of greater than 0.5%. The CGM monitor was worn a mean of 4.262 days a week. None of the subjects reported significant hypoglycemia while wearing the monitor. CGM was effective in improving glycemic control in this population with poorly controlled diabetes.
Digital Commons Citation
Lewis, K R.; McCrone, S; Deiriggi, P; and Bendre, S, "Effectiveness of continuous glucose monitoring in children, adolescents, and young adults with poorly controlled type 1 diabetes" (2017). Clinical and Translational Science Institute. 585.