Semester

Spring

Date of Graduation

1999

Document Type

Thesis

Degree Type

MS

College

School of Dentistry

Department

Not Listed

Committee Chair

C. Russell Jackson.

Abstract

The purpose of this study was to determine if prophylactic oral administration of etodolac would significantly reduce post-endodontic pain, when compared to ibuprofen and a placebo.;Thirty-six patients requiring conventional root canal therapy consented to single blind oral administration of either 400 mg of etodolac, 600 mg of ibuprofen, or a placebo, prior to conventional root canal therapy. Pain evaluation was completed on a pain survey that consisted of visual analog scales at the following time intervals; initial, immediately after, 4 hours, 8 hours, 12 hours, 24 hours, 48 hours, and 72 hours after initiation of root canal therapy.;A significant difference was found for ibuprofen's ability to reduce post-endodontic pain at 4 and 8 hours after initiation of root canal therapy, when compared to etodolac and a placebo (4 Hours P-value = 0.0111; 8 Hours P-value = 0.0397). A significant difference was also found for the periapical diagnosis and the need for additional medication after completion of root canal therapy (P-value = 0.0077).

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