Novel synthesis of 3,4-fused indoles
Date of Graduation
Eberly College of Arts and Sciences
Bjorn C. G. Soderberg.
The goal of this project was to synthesize 3,4-fused indoles having a variety of ring sizes and a variety of functional groups. This has been accomplished by the development of a novel palladium-catalyzed route to 3,4-fused indoles. The key steps are two palladium-catalyzed reactions, an intramolecular Heck reaction followed by a reductive N-heteroannulation. Using this route, a number of 3,4-fused indoles were prepared in acceptable yields.
Hubbard, Jeremiah Wallace, "Novel synthesis of 3,4-fused indoles" (2001). Graduate Theses, Dissertations, and Problem Reports. 1313.