Title

Characterization and application of DMPC-DHPC phospholipid preparations for non-mechanical flow control in microfluidics

Semester

Spring

Date of Graduation

2008

Document Type

Dissertation

Degree Type

PhD

College

Eberly College of Arts and Sciences

Department

Chemistry

Committee Chair

Lisa Holland.

Abstract

The viscosity of aqueous phospholipid mixtures comprised of 1,2-dimyristoyl- sn-glycero-3-phosphocholine (DMPC) and 1,2-dihexanoyl-sn -glycero-3-phosphocholine (DHPC) was characterized with an automated capillary electrophoresis system, as a function of chemical composition, temperature, electric fields, and magnetic fields. This information was then utilized to demonstrate non-mechanical flow control on a microfluidic device based on induced changes in the viscosity of various DMPC-DHPC lipid preparations.

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