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Supported employment approaches may have a significant impact on the Psychosocial experiences of workers with mild and moderate mental retardation. The present study examined the influence of supported employment level (i.e., individual vs. group) on the depression, loneliness, and lifestyle satisfaction of employees participating in a vocational rehabilitation program. It was hypothesized that supported employment level differences would be reflected in the dependent variables of depression, loneliness, and lifestyle satisfaction reported by participants (N = 54). Additional predictions were made about relationships between these dependent variables and measures of social support and social skills. Supported employment level differences on depression, loneliness, and lifestyle satisfaction were not substantiated. There were significant relationships between social skills and depression, social skills and loneliness, and social support and lifestyle satisfaction. Implications for findings are discussed and recommendations for future research are offered.