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School of Medicine




Here, we report a case of a middle-aged woman presenting with severe, long-standing, hyperkeratotic plaques of the lower extremities unrelieved by over-the-counter medications. Initial history and clinical findings were suggestive of an inherited ichthyosis. Ichthyoses are genetic disorders characterized by dry scaly skin and altered skin-barrier function. A diagnosis of ichthyosis vulgaris was confirmed by histopathology. Etiology, prevalence, and treatment options are discussed.

Source Citation

Leight H, Zinn Z, Jalali O. Bilateral lower extremity hyperkeratotic plaques: a case report of ichthyosis vulgaris. Clin Cosmet Investig Dermatol. 2015;8:485-488


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