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College & Research Libraries receives a large number of manuscripts each year that have kept the two of us busy, as editorial assistants, with many of the initial reviews of submission for the journal during the last two years. In 2011 alone C&RL received 134 submissions, of which only 46 were finally selected for publication. This acceptance rate demonstrates the rigor of our review process, but it is coupled with our desire to help prospective authors succeed. There are insights we can offer from our editorial experience that help explain why manuscripts are rejected as well as advice on how to overcome typical problems and barriers we have observed. We would like to frame our insights around the editorial questions we are asked to answer in our initial evaluation of manuscripts.