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Theses/Dissertations from 2020

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Pulmonary immune responses to respirable elongate mineral particles of asbestiform and non-asbestiform morphologies, Timur Khaliullin

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Obese Zucker Rats as a Reverse Translational Model of Human Left Ventricular Hypertrophy, Mackenzie Shelby Newman

Theses/Dissertations from 2019

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Regulator of G Protein Signaling-12 (RGS12) in dopaminergic and kappa opioid receptor-dependent signaling and behavior, Joshua David Gross

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Genetic and Pharmacologic Studies Towards Prevention of opioid use disorder, Shane W. Kaski

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A Study of Gastrointestinal Pathophysiology, Emily Minor

Theses/Dissertations from 2018

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THE MICROVASCULAR AND SYSTEMIC EFFECTS OF TITANIUM DIOXIDE NANOPARTICLE EXPOSURE: A PHYSIOLOGICAL PERSPECTIVE, Alaeddin Bashir Abukabda

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Ex-Vivo Model for Muscle Exposure to Tumor Cell Conditioned Media, Ikttesh K. Chahal

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Welding Fume Exposure and Lung Cancer: Evidence of Lung Toxicity and Tumor Promotion from in vivo Studies in AJ Mice, Lauryn Falcone

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A Study of Epithelial Cl- Secretion in the Murine Distal Colon, Trey S Rottgen

Theses/Dissertations from 2017

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Skeletal Muscle Arteriole Dysfunction and Microvessel Density in Metabolic Syndrome and Depression: How Exercise Can Be Used as an Intervention, Kayla Whitney Branyan

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Effects of Chronic Electronic Vapor Exposure on Body Weight, Appetite, and Metabolism, Matthew J. Breit

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Role of Perivascular Adipose Tissue in Vascular Pathology and the Therapeutic Effect of Exercise, Evan Ray DeVallance

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Effects of Chronic Electronic Cigarette Use on Glucose Metabolism, Hannah Hoskinson

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Cardiac and Mitochondrial Dysfunction during Diabetes Mellitus: Examination of Mitochondrial Import Mechanisms, Danielle Lee Shepherd

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The NAD+-Dependent Histone Deacetylase Sirtuin-2 is Upregulated during Myogenesis and Promotes the Differentiation of C2C12 Myoblasts, David A. Stanton

Theses/Dissertations from 2016

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Interleukin-15 Overexpression Attenuates Muscle Fatigue Associated with Murine EO771 Mammary Tumors, Joseph F. Bohlen

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Voluntary Wheel Running Improves Recovery from Muscle Disuse in Mice, Matthew J. Brooks

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Cerebrovascular Dysfunction in Metabolic Syndrome and Depression: Mechanisms and Implications for Neurovascular Disease, Steven David Brooks

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From association to function: elucidating the role of G Protein Signaling Modulator 3 and variants in its gene locus in rheumatoid arthritis, Bryan Jeffery Gall

Theses/Dissertations from 2015

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Do humans drive spinal cord with limb velocity signal?, Kyla Galbreath

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The Effect of a Community-Based Multi-Lifestyle Intervention on Cardiovascular Health in Rural Populations: A Community-Based Participatory Research Approach, Kyuwan Lee

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Cerium dioxide nanoparticle exposure and microvascular dysfunction: Potential mechanistic links, Valerie C. Minarchick

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Chronic Stress, Depressive Symptoms and Peripheral Vascular Dysfunction: Fundamentals, Mechanisms, Sex Disparities, and Determinants of Integrated Outcomes, Shyla Christine Stanley

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Type 1 Diabetic Heart: Examination of Mitochondrial Structure and MicroRNAs, Dharendra Thapa

Theses/Dissertations from 2014

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Inhibition of arterial KDR channels by DPO-1 and activation of cloned human BK channels by BPA-MS, Ibra S. Fancher IV

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Functional characterization of Phosphodiesterase-4A in behavior and obesity, Rolf T. Hansen III

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Roles of nitric oxide and shear stress in the regulation of microvessel permeability in intact rat mesenteric venules, Sulei Xu

Theses/Dissertations from 2013

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Thrombospondin: An emerging keystone in skeletal muscle structure and function, Gerald Nelson Audet

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Effects of estrogen in an aged animal model of stroke, Rachel L. Leon

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The Role of Neurokinin B in the Regulation of the Preovulatory LH Surge in Ewes, Katrina L. Porter

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Lessons in Modeling, Preventing, and Treating Neural Injury: Improving Bench-to- Bedside Translation, Ryan Coddington Turner

Theses/Dissertations from 2012

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Bisphenol A alters the function and expression of BK channels in vascular smooth muscle through membrane and nuclear signals, Shinichi Asano

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The Role of Clustered Organization and Generation of Mixed Properties in Macaque V2, Clinton Garret Cooper

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Modulation of cardiac pacemaker channels by tyrosine phosphorylation, Jianying Huang

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C-peptide Improves Hyperglycemia-induced Endothelial Redox Balance by Preventing Mitochondrial Oxidative Stress and Enhancing NADPH Synthesis, Himani Vejandla

Roles of eNOS and Nitric Oxide in the Regulation of Microvessel Permeability in Intact Rat Mesenteric Venules, Xueping Zhou

Theses/Dissertations from 2011

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Characterization of the pharmacological effects of digitoxin on lung epithelial cells, Hosam Abdelmonaim Elbaz

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Encoding of Temporal Sound Features in the Rodent Superior Paraolivary Nucleus, Richard A. Felix II

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Vascular Consequences of Metabolic Syndrome Related Shifts in Cyclooxygenase Mediated Arachidonic Acid Metabolism, Adam G. Goodwill

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Molecular Mechanisms of Chromium (VI) - Induced Toxicity and Carcinogenesis, Djordje Medan

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Effects of Age and Early Life Ozone Exposure on the Developmental Dynamics of Afferent Airway Neurons in Postnatal Rats, Leor C. Zellner

Theses/Dissertations from 2010

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Mitochondrial dysfunction in the diabetic heart: Cardioprotection from a novel mitochondrially-targeted therapeutic, Erinne Rose Dabkowski

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Dietary cholesterol effects on learning, memory and amyloid beta: Learning and memory effects on brain cholesterol and sulfatide levels, Deya S. Darwish

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Systemic lipopolysaccharide stimulates airway transepithelial Na+ transport by increasing ENaC and Na+,K+ -pump activity, Michael W. Dodrill

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The Effects of Resveratrol on Oxidative Stress and Muscle Atrophy, Janna Renee Jackson

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The role of nonmuscle Myosin IIA in endothelial cell, Jing Zhu

Theses/Dissertations from 2009

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Role of endothelin 1 in follicular and luteal function in the sheep, Fernando P. Perea-Ganchou

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Effects of aging and exercise training on eNOS uncoupling and reactive oxygen species signaling in the endothelium of skeletal muscle arterioles, Amy L. Sindler

Theses/Dissertations from 2008

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Computer modeling of dapsone-mediated heteroactivation of flurbiprofen metabolism by CYP2C9, Robyn Renee Ayscue

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Caveolin-1 recruitment to the trailing edge of motile cells results in focal adhesion disassembly and nascent interaction with actin stress fibers, Andrew Beardsley

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Putative role of palmitate and Akt signaling in attenuating skeletal muscle growth in the obese zucker rat, Jonathan Michael Peterson

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In vitro elucidation of the metabolic fate of the anticancer drug busulfan, Islam Rasem Younis

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Association of changes in norepinephrine and serotonin transporter expression with the long-term behavioral effects of antidepressant drugs, Zaorui Zhao

Theses/Dissertations from 2007

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Molecular mechanisms of chromium(VI)-induced apoptosis and malignant transformation, Neelam Azad

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Epithelial mechanisms in airway responses induced by hyperosmolarity, Yi Jing

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Expression profiling of oocyte specific genes, transcription factors and microRNAs during early embryonic development in rainbow trout (Onchorhyncus mykiss), Raghuveer K. Ramachandra

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Effects of ovulation of aged follicles, pregnancy diagnosis by ultrasonography, and treatments during lactation on reproduction in ewes, Aimee Kathryn Wurst

Theses/Dissertations from 2006

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Clinically relevant and economic outcomes of maintenance pharmacotherapy in chronic obstructive pulmonary disease (COPD), Anna O. D'Souza

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Modulation of gene expression and DNA adduct formation by chlorophyllin in human mammary cells exposed to benzopyrenes, Kaarthik John

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Esterase inhibition by grapefruit juice and its components leads to newly identified drug interactions, Ping Li

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Oxidative stress in skin induced by chemical and physical agents, Ashley Rebecca Murray

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The extrinsic apoptotic pathway in aged skeletal muscle: Roles of tumor necrosis factor-alpha and interleukin-15, Emidio E. Pistilli

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Effects of environmental factors on the paternal brood pouch and sound production in two sympatric pipefish species from the Chincoteague Bay, Virginia, Jennifer L. Ripley

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Soluble metals of residual oil fly ash alter pulmonary host defense in rats, Jenny Renee Roberts

Theses/Dissertations from 2005

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fMRI studies of amblyopia: Pediatric and adult perspectives, Ian Patrick Conner

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Glutathione conjugation of a cocaine pyrolysis product AEME and related compounds, Alan Lewis Myers

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Cellular mechanisms of luteal regression in the bovine corpus luteum (CL), Aritro Sen

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The effect and mechanism of action of volatile fatty acids on the catabolism of progesterone, Darron Louis Smith

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Factors affecting reproductive efficiency of cattle, Melanie J. Starbuck

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Functional evaluation of cytochrome P450 2D6 allelic isoforms, Weiyan Zhang

Theses/Dissertations from 2004

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Psychophysical studies of binocular and spatial vision in humans with anisometropic and strabismic amblyopia, Ritwick Agrawal

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Interaction between primary alveolar macrophages and primary alveolar type II cells under basal conditions and after lipopolysaccharide or quartz exposure, Rania S. Kanj

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Mechanism of action of NSC3852, a breast cancer differentiation agent, Anna Martirosyan

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Augmentation of the differentiation response to antitumor quinolines, Rayhana Rahim-Bata

Theses/Dissertations from 2003

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On the contribution of MMP-2 and MMP-9 to the postnatal cerebellar corticogenesis, Albert E. Ayoub

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Late embryonic and fetal mortality in the ewe, Alison Brown Dixon

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Metallothionein isoform 3 expression in human bladder urothelium, Seongmi Park

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Cellular specializations for sound localization, Kevin C. Rowland

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Molecular mechanisms of G protein-receptor coupling, Janna Eugenievna Slessareva

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Epileptiform bursting in the disinhibited neonatal cerebral cortex, Jason Eric Wells

Theses/Dissertations from 2002

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Modulation of thiols and pulmonary immune responses due to diesel exhaust particle (DEP) exposure, Nabil Hussain Al-Humadi

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Dendritic development of GABAergic cortical interneurons revealed by biolistic transfection with GFP, Xiaoming Jin

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Anatomical and physiological properties of the superior paraolivary nucleus in the rat, Randy Joseph Kulesza Jr.

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Characterization of metallothionein expression in response to cadmium in the 267-B1, normal prostate cell line, Madhuri G. Neriyanuri

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Antitumor activity of antimalarials in human breast cancer cells, Qun Zhou

Theses/Dissertations from 2001

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Seasonal plasticity of A15 dopaminergic neurons in the ewe, Van Lee Adams

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Prenatal stress alters fear-conditioned behaviors and the response to serotonergic drugs, William C. Griffin III

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Pharmacological regulation of c-myc gene expression in human breast cancer cells, Zaroui Karlen Melkoumian

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Integrated modulation of sympathetic tone in the microcirculation by oxygen, adenosine, and nitric oxide, Bryan Auston Sauls

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Amiodarone-induced pulmonary toxicity in F344 rats, Michael Douglas Taylor

Theses/Dissertations from 2000

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Effects of acetaminophen on estrogen-responsive alkaline phosphatase in Ishikawa endometrial cancer cells, Janet A. Dowdy

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Characterization of the airway epithelial bioelectric mechanisms associated with the effects of epithelium-derived relaxing factor in guinea pig-isolated trachea, Richard Alan Johnston

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Encoding of periodic skin stimuli by spinal dorsal horn neurons, Jeffrey J. Lawson

Theses/Dissertations from 1999

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Androgen-induced norepinephrine release in male accessory sex organ smooth muscle growth and differentiation, Julie M. Kim

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Effects of nicotine on content of corticotropin releasing factor (CRF) in rat amygdala, hypothalamus and brain stem, Sibonisiwe Ntini Masilela

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Characterization of neurotensin's bipolar effects on nociceptive modulation using SR 142948A and SR 48692, two non-peptide neurotensin receptor antagonists, Jeffrey P. Smith

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Acetaminophen stimulates proliferation of breast cancer cells, Eugenia Harnagea Theophilus

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Alterations in intrinsic heart rate in endotoxemia, Peter Drew Wearden

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Alterations of vascular endothelial nitric oxide synthase activity and substrate availability in chronic renal disease, Shen Xiao

Theses/Dissertations from 1998

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Cellular mechanisms of altered neuronal sensitivity in the genetically epilepsy-prone rat, Lance Russell Molnar