Eberly College of Arts and Sciences
Quantum confined materials have been extensively studied for photoluminescent applica- tions. Due to intrinsic limitations of low biocompatibility and challenging modulation, the utilization of conventional inorganic quantum confined photoluminescent materials in bio- imaging and bio-machine interface faces critical restrictions. Here, we present aromatic cyclo-dipeptides that dimerize into quantum dots, which serve as building blocks to further self-assemble into quantum confined supramolecular structures with diverse morphologies and photoluminescence properties. Especially, the emission can be tuned from the visible region to the near-infrared region (420 nm to 820 nm) by modulating the self-assembly process. Moreover, no obvious cytotoxic effect is observed for these nanostructures, and their utilization for in vivo imaging and as phosphors for light-emitting diodes is demon- strated. The data reveal that the morphologies and optical properties of the aromatic cyclo- dipeptide self-assemblies can be tuned, making them potential candidates for supramolecular quantum confined materials providing biocompatible alternatives for broad biomedical and opto-electric applications.
Digital Commons Citation
Tao, Kai; Fan, Zhen; Sun, Leming; Makam, Pandeeswar; Tian, Zhen; Ruegsegger, Mark; Shaham-Niv, Shira; Hansford, Derek; Aizen, Ruth; Pan, Zui; Galster, Scott; Ma, Jianjie; Yuan, Fan; Si, Mingsu; Qu, Songnan; Zhang, Mingjun; Gazit, Ehud; and Li, Junbai, "Quantum confined peptide assemblies with tunable visible to near-infrared spectral range" (2018). Faculty & Staff Scholarship. 1396.
Tao, K., Fan, Z., Sun, L., Makam, P., Tian, Z., Ruegsegger, M., … Li, J. (2018). Quantum confined peptide assemblies with tunable visible to near-infrared spectral range. Nature Communications, 9(1). https://doi.org/10.1038/s41467-018-05568-9
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