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Purpose: To present refractive outcomes from consecutive cases with the Alcon Wavelight® EX500 excimer laser using photorefractive keratectomy (PRK) in patients with high myopia. Methods: A retrospective chart review of consecutive cases of high myopic eyes ($6.0 Diopters [D]) undergoing PRK with the Alcon Wavelight EX500 excimer laser (Alcon Labo- ratories, Fort Worth, TX, USA) was done. Moderately high myopic eyes (6.0 to ,8.0 D [6 D]) were compared with high myopic eyes (8.0 D or greater [8 D]). Outcomes measured included pre- and postoperative refractive error, uncorrected distance visual acuity (UDVA), corrected distance visual acuity, spherical equivalent correction (SEQ), haze incidence, and intraocular pressure (IOP).

Results: One hundred eighteen eyes of 63 patients were evaluated, with 59 eyes having 12 months of follow-up. Thirty-one eyes of 19 patients had 8.0 D or more of myopia. Twelve- month average LogMAR UDVA was −0.06 (20/17) for the 6 D group and −0.08 (20/16) for the 8 D group. Average 12-month SEQ was −0.18 D and preoperatively was −7.52 D for the 6 D group and −0.09 and −9.02 in the 8 D group. Sixty-five eyes (86%) and 24 eyes (96%) had an SEQ within 0.50 D of emmetropia at 3 months in the 6 and 8 D groups, respectively. One eye had visually significant haze developed at 8 months. Three eyes had IOP elevation that resolved with addition of short-term topical IOP-lowering medication.

Conclusion: High myopic PRK with the Alcon Wavelight EX500 excimer laser yields excel- lent refractive outcomes with a low incidence of complications.

Source Citation

Mifflin, M. D., Betts, B. S., Nguyen, J., & Pouly, S. (2018). High myopic photorefractive keratectomy outcomes with the Alcon Wavelight® EX500 excimer laser. Clinical Ophthalmology, Volume 12, 1041–1048.


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