Document Type


Publication Date



School of Medicine


Obstetrics and Gynecology


Undifferentiated endometrial carcinoma, a rare histopathologic diagnosis, has a poor prognosis with high risk of progression during or shortly after completion of adjuvant treatment. We present two cases of undifferentiated endometrial carcinoma: one in a postmenopausal female who experienced recurrent disease immediately after completion of adjuvant treatment and one in a premenopausal female who experienced disease progression while receiving adjuvant treatment. These cases exemplify the aggressive behavior of undifferentiated endometrial carcinoma and suggest the need for a more effective treatment in the upfront setting than the current standard of care for endometrioid endometrial adenocarcinoma.

Source Citation

Pfaendler, K. S., & Randall, L. M. (2019). Rapid progression of disease in two cases of undifferentiated endometrial carcinoma. Gynecologic Oncology Reports, 27, 65–68.


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