Theses/Dissertations from 2023
Elucidating mechanisms of proteasome modulation by small molecules to treat neurodegenerative diseases and cancer, Janelle Joo Yee Chuah
Longitudinal oxygen imaging in 3D (bio)printed models, Ryan Curtis O'Connell
The role of NEDD9 in HER2-driven breast cancer., Marc Louis Purazo
Investigating the Role of NUDT7-mediated Peroxisomal CoA Degradation in the Regulation of Hepatic CoA Levels and Lipid Metabolism, Schuyler Dan Adams Vickers
Theses/Dissertations from 2022
Actin Cytoskeletal Regulation and Matrix Metalloproteinase Targeting in Head and Neck Squamous Cell Carcinoma (HNSCC) Progression, Jessica Lea Allen
ERO1α Promotes Tumorigenesis in EGFR Driven NSCLC, brennan d. johnson
The Musashi RNA Binding Proteins Are Regulators of Alternative Splicing and Protein Expression in Photoreceptor Cells, Fatimah Kh. Matalkah
Transitions Between the Steps of Group IIC Intron Forward and Reverse Splicing and Integration into DNA, Claire Mae Smathers
Elucidating the Proteasomal Regulatory Mechanism of Proteasome Activator PA28γ /REGγ, Taylor Ann Thomas
Theses/Dissertations from 2020
Characterization of the Biochemical Properties of Nudt8, a Novel CoA-degrading Enzyme that Localizes to the Mitochondria, Evan W. Kerr
Grainyhead-like 2 Sensitizes Cells to Natural Killer Cell Cytotoxicity and Promotes the Interferon Response, Ian Philip MacFawn
Novel Roles of Tobacco-associated Genes Underlying Disparate Survival in Appalachian Head and Neck Squamous Cell Carcinoma, Brenen William Papenberg
c-Jun NH2-terminal kinase signaling controls cellular mechanisms of guided cortical interneuron migration, Skye Eleanor Smith
Theses/Dissertations from 2019
Glial cell expansion and intercellular signaling in the developing Medial Nucleus of the Trapezoid Body (MNTB), Ashley N. Brandebura
Induction of cerebral hyperexcitability by peripheral viral challenge: Role of CXCL10 chemokine, Tiffany J. Petrisko
Determining the Role of Nudt7 in the Regulation of Cellular CoA Levels and Metabolism, Stephanie Anne Shumar
Alternative Splicing in Vertebrate Photoreceptors and Mechanisms Underlying Retinitis Pigmentosa, Jesse C. Sundar
Elucidating a Common Mechanism of Proteasome Impairment in Neurodegenerative Disease and its Pharmacological Intervention, Tiffany Ann Thibaudeau
Theses/Dissertations from 2018
Ergot Alkaloid Synthetic Capacity of Penicillium camemberti, Samantha J. Fabian
Cortactin Phosphorylation by Casein Kinase 2 Regulates Actin Related Protein 2/3 Complex Activity and Invadopodia Function, Steven Michael Markwell
ARL2BP, a novel ciliopathy protein, is required for cilia microtubule formation, Abigail Ruth Moye
Proteasomal ATPases Hard at Work: The Inner Workings of a Protein Destruction Machine., Aaron M. Snoberger
Theses/Dissertations from 2017
Novel Mechanisms Controlling the Expression of the Antidiabetic Hepatokine Fibroblast Growth Factor 21, Kimberly M. Alonge
Interactions between Euwallacea Ambrosia Beetles, Their Fungal Symbionts and the Native Trees They Attack in the Eastern United States, Matthew C. Berger
Identification of SNPs Potentially Associated with Asthma Using a Di-isocyanate Luciferase Reporter Assay, Wentao Jiang
Dual Targeting of the Mesenchymal and Amoeboid Pathways: A Viable Therapy against Metastatic Breast Cancer, Brandon C. Jones
Diversity and Function of Fungi Associated with the Fungivorous Millipede, Brachycybe lecontii, Angie M. Macias
Theses/Dissertations from 2016
Grainyhead-like 2 Reverses the Metabolic Changes Induced by the Oncogenic Epithelialmesenchymal Transition: Effects on Anoikis, Joshua C. Farris
The role of NAD(P)H:quinone oxidoreductase 1 in non-small cell lung cancer tumorigenesis and lung cancer stem cell maintenance, Brian Madajewski
SHP2 promotes Triple Negative Breast Cancer by mediating crosstalk between EGFR and Wnt beta-catenin signaling pathways, Elisha Martin
The Regulation of Alternative Pre-mRNA Splicing in Photoreceptor Cells., Daniel P. Murphy
Grainyhead-like-2 inhibits the co-activator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition, Phillip M. Pifer
Comparisons of host susceptibility to isogenic virulent and hypovirulent [CHV1-infected] strains of Cryphonectria parasitica among Castanea hosts and plant tissue types, Cameron M. Stauder
Hydrogeochemical Characterization of Rural Drinking Water in the Gauley River Basin, Monongahela National Forest, Arati A. Umarvadia
Theses/Dissertations from 2015
Phylogenetic relationships among arbuscular mycorrhizal fungal species in the deeply rooted archaeosporales (Glomeromycota), Robert J. Bills
Identification of a critical gene in the dihydroergot alkaloid pathway, Yulia Bilovol
Saprophytic Colonization and Sporulation of Virulent and Hypovirulent Cryphonectria parasitica on American Chestnut (Castanea dentata) and Scarlet Oak (Quercus coccinea), Eric Shelton Goddard
Investigations of Pasteuria and the Root-Lesion Nematode Pratylenchus penetrans in Soils Collected from Certified Organic Farms in the Mid-Atlantic United States, Tiara Nicole King
Enhancement of RNA Splicing by the Nutrient-Regulated Splicing Factor SRSF3, Amanda L. Suchanek
Microbiology in Shale: Alternatives for Enhanced Gas Recovery, Yael Tarlovsky Tucker
Interactions of brown marmorated stink bug, Colletotrichum acutatum and trap crops in organic tomato production, Robert James Voshell
Theses/Dissertations from 2014
Biomass production, composition, and ethanol potential of switchgrass grown on reclaimed surface mines in West Virginia, Carol A. Brown
Analysis and Interpretation of Complex Biological Signal Transduction Networks, Holly N. Currie
Peripheral challenge with a viral mimic elicits seizure hypersusceptibility, Lindsay Tanis Michalovicz
Theses/Dissertations from 2013
Survival, injury, and antibiotic resistance patterns of Cronobacter sakazakii and Escherichia coli resulting from exposure to low-temperature ground water, Alisha L. Dailey
Exploring the mechanism of SHP2 and EGFR/HER2 cooperation in breast cancer cell signaling, Zachary Raymond Hartman
Thrombelastography Parameters versus Classical Coagulation Profile in Trauma Patients: a Retrospective Study, Abdulraouf Y. Lamoshi
Phosphorus Retention and Transformation in Floodplain Forests of the Southeastern United States, John A. Navaratnam
The evolution of the paleopolyploid genome in family Salicaceae, Eli Rodgers-Melnick
Characterization of genes involved in sumoylation during embryogenesis in rainbow trout (Oncorhynchus mykiss), Xiaowei Zang
Theses/Dissertations from 2012
The role of Src-homology 2 domain-containing tyrosine phosphatase 2 in signaling and tumorigenesis of basal type/triple negative breast cancer, Fatimah Kh. Matalkah
Role of Chaperonin CCT in G-protein Biosynthesis, Catherine Woodard
Theses/Dissertations from 2011
Can changes in SR protein acetylation affect alternative splicing?, Heather E. Knupp
Characterization and genetic manipulation of ergot pathway inefficiency in fungi, Prashanthi Mulinti
Functional Analysis and Post-Transcriptional Regulation of Oocyte-Specific Transcription Factors During Early Embryogenesis in Cattle, Swamy Krishna Tripurani
Theses/Dissertations from 2009
Ergot alkaloid biosynthesis in Aspergillus fumigatus : Association with sporulation and clustered genes common among ergot fungi, Christine M. Coyle
The identification of molecular guidance cues necessary for development of the central auditory system, David M. Howell
The roles of the phosducin family proteins in the regulation of heterotrimeric G proteins in vertebrate photoreceptors, Hongman Song
The effect of nutrients upon the activity of SR proteins, Callee McConnell Walsh
Cryptic subtelomeric rearrangements and studies of telomere length, Jasen Lee Wise
Functional analysis of Arabidopsis cold shock domain proteins, Yongil Yang
Functions of Rx in early vertebrate ocular development, Brian G. Zamora
Theses/Dissertations from 2007
Analysis of motor activity of recombinant myosin-1c, Anindita Biswas
Characterization of myosin I in the inner ear, Kelli R. Phillips
Theses/Dissertations from 2006
Differential binding of hnRNP K, L and A2/B1 to an exonic splicing silencer element located within exon 12 of glucose -6 -phosphate dehydrogenase mRNA, Brian Nelson Griffith
Tumor necrosis factor-alpha production induced by peptidoglycan-polysaccharide in early pregnant ewes, Gabrielle Marie Rogers
Signaling pathways involved in regulation of glucose -6 -phosphate dehydrogenase (G6PD) by arachidonic acid, Indrani Talukdar
Analysis of the mechanisms mediating the regulation of acetyl -CoA carboxylase transcription by the liver X receptor and chenodeoxycholic acid, Saswata Talukdar
Theses/Dissertations from 2005
The molecular mechanisms underlying 6-hydroxydopamine and ethanol-induced neurotoxicity, Gang Chen
Determination of Rx expression in the adult mouse retina and delineation of the Rx mediated gene regulation, Supriya A. Shah
Theses/Dissertations from 2004
Exposures to silica and inducers of xenobiotic metabolism in the rat lung, Lori A. Battelli
Insertion of genes and operons into the Escherichia coli genome through targeted recombination, Dennis Coss
Theses/Dissertations from 2003
Metallothionein gene expression in human breast cancer, Volkan Gurel
Molecular mechanisms of G protein-receptor coupling, Hongzheng Ma
Cytogenetic analysis of primary breast tumors and MCF10A cells to determine early steps of breast carcinoma, Mohammad Mah Odetallah
Gene expression profiling in prepubertal and adult male mice using cDNA and oligonucleotide microarrays, Lisa Marie Tomascik-Cheeseman
Molecular cytogenetic evaluation of uveal melanoma cell lines and archival tissue, Jason Scott White
Theses/Dissertations from 2002
Thermodynamic effects of phospholamban on Ca-ATPase kinetics, Patrick L. Apopa
In vitro genotoxicity investigations of jet fuel, Shawna M. Jackman
Stress response genes in the human proximal tubules, Doyeob Kim
Role of protein kinase C isoforms in human breast tumor cell survival, Meredith Ann McCracken
Theses/Dissertations from 2001
Green tea antioxidants inhibition of oxidation and mutation, Paul Stout McConnell
Higher order chromatin degradation induced by hydrogen peroxide in glial cells, Raymond Mouzannar
Genetic evaluation of cytochrome P450 expression in smoking and nonsmoking women, Satya Vijayanand Vadlamuri
Theses/Dissertations from 2000
Evaluation of maternal serum triple screen as an identifier of trisomy 21 pregnancy, Jonnie Ann Lane
Studies of the respiratory chain of Methylococcus capsulatus (Bath), Timothy Brian Miley
Structural determinants of murine leukemia virus reverse transcriptase that are important for template switching, fidelity, and drug resistance, Evguenia S. Svarovskaia
Theses/Dissertations from 1999
Differences in lipoxygenase activity as related to cultivar differences in superficial scald of apples, Judith Lynne Hercules Reynolds
Regulation of glucose -6 -phosphate dehydrogenase by polyunsaturated fatty acids in cultured rat hepatocytes, Laura Petrosky Stabile