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Theses/Dissertations from 2020

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Role of ciliary proteins ADP Ribosylation Factor Like GTPase 13B (ARL13B) and Bardet-Biedl Syndrome-8 (BBS8) in photoreceptor outer segment morphogenesis, maintenance, and viability, Tanya L. Dilan

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Characterization of the Biochemical Properties of Nudt8, a Novel CoA-degrading Enzyme that Localizes to the Mitochondria, Evan W. Kerr

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Grainyhead-like 2 Sensitizes Cells to Natural Killer Cell Cytotoxicity and Promotes the Interferon Response, Ian Philip MacFawn

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Novel Roles of Tobacco-associated Genes Underlying Disparate Survival in Appalachian Head and Neck Squamous Cell Carcinoma, Brenen William Papenberg

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c-Jun NH2-terminal kinase signaling controls cellular mechanisms of guided cortical interneuron migration, Skye Eleanor Smith

Theses/Dissertations from 2019

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Glial cell expansion and intercellular signaling in the developing Medial Nucleus of the Trapezoid Body (MNTB), Ashley N. Brandebura

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Induction of cerebral hyperexcitability by peripheral viral challenge: Role of CXCL10 chemokine, Tiffany J. Petrisko

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Determining the Role of Nudt7 in the Regulation of Cellular CoA Levels and Metabolism, Stephanie Anne Shumar

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Alternative Splicing in Vertebrate Photoreceptors and Mechanisms Underlying Retinitis Pigmentosa, Jesse C. Sundar

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Elucidating a Common Mechanism of Proteasome Impairment in Neurodegenerative Disease and its Pharmacological Intervention, Tiffany Ann Thibaudeau

Theses/Dissertations from 2018

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Ergot Alkaloid Synthetic Capacity of Penicillium camemberti, Samantha J. Fabian

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Cortactin Phosphorylation by Casein Kinase 2 Regulates Actin Related Protein 2/3 Complex Activity and Invadopodia Function, Steven Michael Markwell

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ARL2BP, a novel ciliopathy protein, is required for cilia microtubule formation, Abigail Ruth Moye

Theses/Dissertations from 2017

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Novel Mechanisms Controlling the Expression of the Antidiabetic Hepatokine Fibroblast Growth Factor 21, Kimberly M. Alonge

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Interactions between Euwallacea Ambrosia Beetles, Their Fungal Symbionts and the Native Trees They Attack in the Eastern United States, Matthew C. Berger

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Identification of SNPs Potentially Associated with Asthma Using a Di-isocyanate Luciferase Reporter Assay, Wentao Jiang

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Dual Targeting of the Mesenchymal and Amoeboid Pathways: A Viable Therapy against Metastatic Breast Cancer, Brandon C. Jones

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Diversity and Function of Fungi Associated with the Fungivorous Millipede, Brachycybe lecontii, Angie M. Macias

Theses/Dissertations from 2016

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Grainyhead-like 2 Reverses the Metabolic Changes Induced by the Oncogenic Epithelialmesenchymal Transition: Effects on Anoikis, Joshua C. Farris

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The role of NAD(P)H:quinone oxidoreductase 1 in non-small cell lung cancer tumorigenesis and lung cancer stem cell maintenance, Brian Madajewski

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SHP2 promotes Triple Negative Breast Cancer by mediating crosstalk between EGFR and Wnt beta-catenin signaling pathways, Elisha Martin

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The Regulation of Alternative Pre-mRNA Splicing in Photoreceptor Cells., Daniel P. Murphy

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Grainyhead-like-2 inhibits the co-activator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition, Phillip M. Pifer

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Comparisons of host susceptibility to isogenic virulent and hypovirulent [CHV1-infected] strains of Cryphonectria parasitica among Castanea hosts and plant tissue types, Cameron M. Stauder

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Hydrogeochemical Characterization of Rural Drinking Water in the Gauley River Basin, Monongahela National Forest, Arati A. Umarvadia

Theses/Dissertations from 2015

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Phylogenetic relationships among arbuscular mycorrhizal fungal species in the deeply rooted archaeosporales (Glomeromycota), Robert J. Bills

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Identification of a critical gene in the dihydroergot alkaloid pathway, Yulia Bilovol

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Saprophytic Colonization and Sporulation of Virulent and Hypovirulent Cryphonectria parasitica on American Chestnut (Castanea dentata) and Scarlet Oak (Quercus coccinea), Eric Shelton Goddard

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Investigations of Pasteuria and the Root-Lesion Nematode Pratylenchus penetrans in Soils Collected from Certified Organic Farms in the Mid-Atlantic United States, Tiara Nicole King

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Enhancement of RNA Splicing by the Nutrient-Regulated Splicing Factor SRSF3, Amanda L. Suchanek

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Microbiology in Shale: Alternatives for Enhanced Gas Recovery, Yael Tarlovsky Tucker

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Interactions of brown marmorated stink bug, Colletotrichum acutatum and trap crops in organic tomato production, Robert James Voshell

Theses/Dissertations from 2014

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Biomass production, composition, and ethanol potential of switchgrass grown on reclaimed surface mines in West Virginia, Carol A. Brown

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Analysis and Interpretation of Complex Biological Signal Transduction Networks, Holly N. Currie

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Peripheral challenge with a viral mimic elicits seizure hypersusceptibility, Lindsay Tanis Michalovicz

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Elucidation of the early steps of ergot alkaloid synthesis by pathway reconstruction in Aspergillus nidulans, Katy Ryan

Theses/Dissertations from 2013

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Survival, injury, and antibiotic resistance patterns of Cronobacter sakazakii and Escherichia coli resulting from exposure to low-temperature ground water, Alisha L. Dailey

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Exploring the mechanism of SHP2 and EGFR/HER2 cooperation in breast cancer cell signaling, Zachary Raymond Hartman

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Thrombelastography Parameters versus Classical Coagulation Profile in Trauma Patients: a Retrospective Study, Abdulraouf Y. Lamoshi

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Phosphorus Retention and Transformation in Floodplain Forests of the Southeastern United States, John A. Navaratnam

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The evolution of the paleopolyploid genome in family Salicaceae, Eli Rodgers-Melnick

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Characterization of genes involved in sumoylation during embryogenesis in rainbow trout (Oncorhynchus mykiss), Xiaowei Zang

Theses/Dissertations from 2012

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The role of Src-homology 2 domain-containing tyrosine phosphatase 2 in signaling and tumorigenesis of basal type/triple negative breast cancer, Fatimah Kh. Matalkah

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Role of Chaperonin CCT in G-protein Biosynthesis, Catherine Woodard

Theses/Dissertations from 2011

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Can changes in SR protein acetylation affect alternative splicing?, Heather E. Knupp

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Characterization and genetic manipulation of ergot pathway inefficiency in fungi, Prashanthi Mulinti

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Functional Analysis and Post-Transcriptional Regulation of Oocyte-Specific Transcription Factors During Early Embryogenesis in Cattle, Swamy Krishna Tripurani

Theses/Dissertations from 2009

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Ergot alkaloid biosynthesis in Aspergillus fumigatus : Association with sporulation and clustered genes common among ergot fungi, Christine M. Coyle

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The identification of molecular guidance cues necessary for development of the central auditory system, David M. Howell

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The roles of the phosducin family proteins in the regulation of heterotrimeric G proteins in vertebrate photoreceptors, Hongman Song

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The effect of nutrients upon the activity of SR proteins, Callee McConnell Walsh

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Cryptic subtelomeric rearrangements and studies of telomere length, Jasen Lee Wise

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Functional analysis of Arabidopsis cold shock domain proteins, Yongil Yang

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Functions of Rx in early vertebrate ocular development, Brian G. Zamora

Theses/Dissertations from 2007

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Analysis of motor activity of recombinant myosin-1c, Anindita Biswas

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Characterization of myosin I in the inner ear, Kelli R. Phillips

Theses/Dissertations from 2006

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Differential binding of hnRNP K, L and A2/B1 to an exonic splicing silencer element located within exon 12 of glucose -6 -phosphate dehydrogenase mRNA, Brian Nelson Griffith

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Tumor necrosis factor-alpha production induced by peptidoglycan-polysaccharide in early pregnant ewes, Gabrielle Marie Rogers

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Signaling pathways involved in regulation of glucose -6 -phosphate dehydrogenase (G6PD) by arachidonic acid, Indrani Talukdar

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Analysis of the mechanisms mediating the regulation of acetyl -CoA carboxylase transcription by the liver X receptor and chenodeoxycholic acid, Saswata Talukdar

Theses/Dissertations from 2005

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The molecular mechanisms underlying 6-hydroxydopamine and ethanol-induced neurotoxicity, Gang Chen

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Heat shock protein 70 as an indicator of toxic heavy metal exposure and oxidative stress in the serum of asymptomatic shipyard welders, Sung Gu Han

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Determination of Rx expression in the adult mouse retina and delineation of the Rx mediated gene regulation, Supriya A. Shah

Theses/Dissertations from 2004

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Exposures to silica and inducers of xenobiotic metabolism in the rat lung, Lori A. Battelli

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Insertion of genes and operons into the Escherichia coli genome through targeted recombination, Dennis Coss

Theses/Dissertations from 2003

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Metallothionein gene expression in human breast cancer, Volkan Gurel

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Molecular mechanisms of G protein-receptor coupling, Hongzheng Ma

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Cytogenetic analysis of primary breast tumors and MCF10A cells to determine early steps of breast carcinoma, Mohammad Mah Odetallah

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Gene expression profiling in prepubertal and adult male mice using cDNA and oligonucleotide microarrays, Lisa Marie Tomascik-Cheeseman

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Molecular cytogenetic evaluation of uveal melanoma cell lines and archival tissue, Jason Scott White

Theses/Dissertations from 2002

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Thermodynamic effects of phospholamban on Ca-ATPase kinetics, Patrick L. Apopa

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In vitro genotoxicity investigations of jet fuel, Shawna M. Jackman

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Stress response genes in the human proximal tubules, Doyeob Kim

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Role of protein kinase C isoforms in human breast tumor cell survival, Meredith Ann McCracken

Theses/Dissertations from 2001

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Green tea antioxidants inhibition of oxidation and mutation, Paul Stout McConnell

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Higher order chromatin degradation induced by hydrogen peroxide in glial cells, Raymond Mouzannar

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Genetic evaluation of cytochrome P450 expression in smoking and nonsmoking women, Satya Vijayanand Vadlamuri

Theses/Dissertations from 2000

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Evaluation of maternal serum triple screen as an identifier of trisomy 21 pregnancy, Jonnie Ann Lane

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Studies of the respiratory chain of Methylococcus capsulatus (Bath), Timothy Brian Miley

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Structural determinants of murine leukemia virus reverse transcriptase that are important for template switching, fidelity, and drug resistance, Evguenia S. Svarovskaia

Theses/Dissertations from 1999

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Differences in lipoxygenase activity as related to cultivar differences in superficial scald of apples, Judith Lynne Hercules Reynolds

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Regulation of glucose -6 -phosphate dehydrogenase by polyunsaturated fatty acids in cultured rat hepatocytes, Laura Petrosky Stabile