Effect of increased energy in a restricted diet on bone mineral composition and breaking load of young rat tibias
Date of Graduation
Davis College of Agriculture, Natural Resources and Design
Human Nutrition and Foods
M. Z. A. Nomani.
Osteoporosis is a major health problem in the United States and those that are on energy restricted diets such as anorectic subjects. Thirty Wistar strain, young male rats were fed diets with varying quantities of fat for a period of four weeks (energy intake 67--75% of requirement). The rat tibias' physical properties were measured. Bone mineral composition testing was conducted for calcium, magnesium, and phosphorus, on the tibia shaft. There were no significant differences among the parameters of length, diameter, volume, density, bone bending (elasticity), fracture load, and minerals between experimental diets. There was a negative association between bending and bone density (r - 0.48, p < 0.01). Density was also positively associated with calcium, magnesium, and phosphorus in the tibia shaft (r 0.83, 0.87, 0.93, respectively, p < 0.01) per unit volume (p < 0.01). Further studies on energy supplementation along with calcium and vitamin D under energy restricted conditions are suggested.
Romanchak, Marcia Ann, "Effect of increased energy in a restricted diet on bone mineral composition and breaking load of young rat tibias" (2002). Graduate Theses, Dissertations, and Problem Reports. 1495.