Date of Graduation


Document Type


Degree Type



School of Dentistry


Not Listed

Committee Chair

Michael D. Bagby.


The purpose of this study was to compare the solubility of four sealers in three common endodontic solvents at time intervals of five minutes, ten minutes, and twenty minutes. Recently, there has been a growing number of resin endodontic sealers with multiple studies looking at leakage and very few investigating their solubility. Three resin sealers (AH Plus, Epiphany, and EndoREZ) and one Grossman's formula sealer (Roth's 801) were tested with three common endodontic solvents (Chloroform, Eucalyptol, Endosolv-R). All sealers were mixed according to the manufactors' specifications and placed into metal rings with openings of a diameter of twenty millimeters and height of two millimeters. Forty five samples of each sealer were allowed to set up for at least forty eight hours at thirty seven degrees Celsius with moisture present. A sample size of five was randomly assigned to one of the three solvents and one of the three time groups. The samples were weighed to the 0.0001 gram before being placed in the solvent. After being in the solvent, the samples were allowed to dry for twenty four hours before taking the final weight. An Excel spreadsheet was used to organize the data and calculate the differences in weight. The data was analyzed in a Split Plot ANOVA employing the REML method and Tukey's HSD. This was accomplished, by using the Jump software. Significance was determined at P < 0.05. The results indicated that multiple factors were significant, including solvent, sealer, and the amount of time. Chloroform was the most effective solvent and was the strongest at the twenty minutes time frame. As for the sealers, AH Plus and Roth's 801 were the most soluble sealers. Eucalyptol was effective only on Roth's 801. The results of this study show that Epiphany and EndoREZ are not appreciably soluble and Endosolv-R was not clinically effective on any of the four sealers..