Yang He



Date of Graduation


Document Type

Problem/Project Report

Degree Type



Statler College of Engineering and Mineral Resources


Mechanical and Aerospace Engineering

Committee Chair

Edward Sabolsky

Committee Co-Chair

Konstantinos A, Sierros

Committee Member

Terence Musho


To date, malignancies have been categorized as one of the leading life-threatening diseases worldwide, mainly because of lack of imaging devices for detection of cancers at its early stage of development. In this case, the emergence of novel strategies which can be effectively used in early stage cancer detection and therapy continue to become an inevitable need and indispensable scope of and cancer field researchers, for which implementation of new technologies are required to advance the early detection and management of cancers. The biomedical imaging of the organs in the living system offers a viable approach to label and image the cells. Among the different bioimaging techniques such as X-ray, Commuted Tomography, Emission Tomography and Magnetic Resonance Imaging that have been developed, Quantum-Dots based technique has acquired increasing attention because of its unique optical and electrical properties and good biocompatibility. In this report the synthesis of ZnSe@ZnS core-shell Quantum Dots, which is cadmium-free and non-toxic to the biological cells, is proposed. These core-shell Quantum Dots will be applicable to biomedical imaging and diagnostics operating on living biological cells.

Embargo Reason

Patent Pending