Plasmon-Enhanced Optical Probes for Sensing of Drug Metabolite

Author

Jennifer Boryczka, West Virginia UniversityFollow

Semester

Summer

Date of Graduation

2020

Document Type

Thesis

Degree Type

MS

College

Statler College of Engineering and Mineral Resources

Department

Mechanical and Aerospace Engineering

Committee Chair

Nianqiang Wu

Committee Member

Kostas Sierros

Committee Member

Yon Rojanasakul

Abstract

An Au@SiO₂ core-shell nanostar structure was synthesized along with CuInS2 quantum dots. The quantum dots display near-infrared fluorescence. In this work, the nanostar structure was functionalized with antibodies and then was utilized as a SERS probe for drug metabolite detection. Drugs are an illicit substance that police, medics, and hospitals need to know if an individual is under the influence of but that individual will not always be willing or able to provide that information. A sensor based on this new probe has been developed for detection of drug metabolites in buffer.

Recommended Citation

Boryczka, Jennifer, "Plasmon-Enhanced Optical Probes for Sensing of Drug Metabolite" (2020). Graduate Theses, Dissertations, and Problem Reports. 7686.
https://researchrepository.wvu.edu/etd/7686