Extramedullary Solitary Plasmacytoma: Demonstrating the Role of 18F-FDG PET Imaging

Authors

Archana Gautam, Mayo Clinic
Kamal K. Sahu, Mayo Clinic
Ahsan Alamgir, West Virginia University
Imran Siddiqi, University of Southern California
Sikander Ailawadhi, Mayo Clinic

Document Type

Article

Publication Date

2017

College/Unit

School of Medicine

Department/Program/Center

Medicine

Abstract

An Extramedullary Plasmacytoma (EMP) is characterized by a neoplastic proliferation of clonal plasma cells outside the medullary cavity. EMPs are a rare occurrence compared to other malignant plasma cell disorders and account for approximately 3-5% of plasma-cell neoplasms. Although most cases of EMP are not immediately life threatening at diagnosis, EMPs can progress to Multiple Myeloma (MM) and thus, warrant monitoring. Currently, there are no standard guidelines for when and how to monitor patients who are diagnosed with or treated for a solitary plasmacytoma. We present a case of solitary EMP who was treated adequately and definitively but developed a distinct, non-contiguous subsequent solitary EMP and was only discovered due to surveillance ¹⁸F-Fludeoxyglucose Positron Emission Tomography (¹⁸F-FDG) (PET) scan. Uniform surveillance guidelines should be developed and the potential benefits of PET and other imaging techniques as well as their cost should be considered.

Digital Commons Citation

Gautam, Archana; Sahu, Kamal K.; Alamgir, Ahsan; Siddiqi, Imran; and Ailawadhi, Sikander, "Extramedullary Solitary Plasmacytoma: Demonstrating the Role of 18F-FDG PET Imaging" (2017). Faculty & Staff Scholarship. 1728.
https://researchrepository.wvu.edu/faculty_publications/1728

Source Citation

Gautam, A. (2017). Extramedullary Solitary Plasmacytoma: Demonstrating the Role of 18F-FDG PET Imaging. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH. https://doi.org/10.7860/jcdr/2017/22801.9557