Document Type

Article

Publication Date

2017

College/Unit

School of Medicine

Department/Program/Center

Medicine

Abstract

Dermatomyositis (DM) is a unique inflammatory myopathy with clinical findings of proximal muscle weakness, characteristic rash, and elevated muscle enzymes. The association of DM and malignancy, most commonly adenocarcinoma, is well known. There have been few case reports of primary myelofibrosis associated with DM. We present the case of a 69-year-old male with a history of polycythemia vera (PV) who developed proximal muscle weakness, dysphagia, and rash. He was found to have elevated creatinine kinase and skin biopsy was consistent with DM. Due to persistent pancytopenia a bone marrow biopsy was performed and showed postpolycythemic myelofibrosis. To our knowledge, this is the first case reported of this unique association.

Source Citation

Fei, N., & Sofka, S. (2017). Dermatomyositis Associated with Myelofibrosis following Polycythemia Vera. Case Reports in Hematology, 2017, 1–4. https://doi.org/10.1155/2017/9091612

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