Author ORCID Identifier
https://orcid.org/0000-0002-5968-0245
https://orcid.org/0000-0002-2818-840X
N/A
Document Type
Article
Publication Date
2012
College/Unit
School of Medicine
Department/Program/Center
Medicine
Abstract
Background. Prediabetes is a preclinical stage in the hyperglycemia continuum where subjects are at increased risk of developing diabetes. Several studies reported a positive association between markers of sleep-disordered breathing (SDB) and diabetes. However, few studies investigated the relationship between SDB markers and prediabetes. Methods. We examined 5,685 participants ≥20 years from the National Health and Nutrition Examination Survey (NHANES) 2005–2008. The exposure of interest was SDB markers including sleep duration, snoring, snorting, and daytime sleepiness. The outcome was prediabetes (), among subjects free of diabetes. Results. SDB markers were associated with prediabetes. Compared to those without any sleep disturbance, the multivariable odds ratio (OR) (95% confidence interval (CI)) of prediabetes among those with three or more SDB markers was 1.69 (1.28–2.22). In subgroup analyses, the association between SDB markers and prediabetes was stronger among women (OR (95% CI) = 2.09 (1.36–3.23) when compared to men (1.52 (1.00–2.35)) and was present among non-Hispanic whites (2.66 (1.92–3.69)) and Mexican Americans (1.99 (1.13–3.48)), but not among non-Hispanic blacks (1.10 (0.70–1.73)). Conclusion. SDB markers were associated with prediabetes. This association was stronger in women and was present mainly in non-Hispanic whites and Mexican Americans.
Digital Commons Citation
Alshaarawy, Omayma; Teppala, Srinivas; and Shankar, Anoop, "Markers of Sleep-Disordered Breathing and Prediabetes in US Adults" (2012). Faculty & Staff Scholarship. 2714.
https://researchrepository.wvu.edu/faculty_publications/2714
Source Citation
Alshaarawy, O., Teppala, S., & Shankar, A. (2012). Markers of Sleep-Disordered Breathing and Prediabetes in US Adults. International Journal of Endocrinology, 2012, 1–8. https://doi.org/10.1155/2012/902324
Comments
Copyright © 2012 Omayma Alshaarawy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.