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Theses/Dissertations from 2023

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INFLUENCE OF MATERNAL NANO-TITANIUM DIOXIDE INHALATION EXPOSURE ON CYCLOOXYGENASE METABOLITES: MATERNAL MICROVASCULAR AND SEXUALLY DIMORPHIC FETO-PLACENTAL OUTCOMES., Julie Anne Griffith

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Investigation of Regulator of G Protein Signaling-12 (RGS12) as a Modulator of Monoamine Transporters and Behavioral Responses to Cocaine, Allison Noel White

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Xanthine Oxidase-Induced Vascular Dysfunction in Nano-TiO2 Inhalation, Xena Marie Williams

Theses/Dissertations from 2022

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Investigating the mitochondrial protein mitoNEET in C. elegans models of aging and Alzheimer's disease, Jacob Ryan Boos

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Microvascular Consequences of Engineered Nanomaterial Inhalation Exposure and Subsequent Reproductive Outcomes, Krista Lee Garner

Theses/Dissertations from 2021

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Novel mechanisms of neuronal and hormonal regulation of large intestinal electrolyte transport, Andrew John Nickerson

Theses/Dissertations from 2020

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Pulmonary immune responses to respirable elongate mineral particles of asbestiform and non-asbestiform morphologies, Timur Khaliullin

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Obese Zucker Rats as a Reverse Translational Model of Human Left Ventricular Hypertrophy, Mackenzie Shelby Newman

Theses/Dissertations from 2019

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Regulator of G Protein Signaling-12 (RGS12) in dopaminergic and kappa opioid receptor-dependent signaling and behavior, Joshua David Gross

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Genetic and Pharmacologic Studies Towards Prevention of opioid use disorder, Shane W. Kaski

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A Study of Gastrointestinal Pathophysiology, Emily Minor

Theses/Dissertations from 2018

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The Microvascular And Systemic Effects Of Titanium Dioxide Nanoparticle Exposure: A Physiological Perspective, Alaeddin Bashir Abukabda

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Ex-Vivo Model for Muscle Exposure to Tumor Cell Conditioned Media, Ikttesh K. Chahal

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Welding Fume Exposure and Lung Cancer: Evidence of Lung Toxicity and Tumor Promotion from in vivo Studies in AJ Mice, Lauryn Falcone

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A Study of Epithelial Cl- Secretion in the Murine Distal Colon, Trey S Rottgen

Theses/Dissertations from 2017

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Skeletal Muscle Arteriole Dysfunction and Microvessel Density in Metabolic Syndrome and Depression: How Exercise Can Be Used as an Intervention, Kayla Whitney Branyan

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Effects of Chronic Electronic Vapor Exposure on Body Weight, Appetite, and Metabolism, Matthew J. Breit

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Role of Perivascular Adipose Tissue in Vascular Pathology and the Therapeutic Effect of Exercise, Evan Ray DeVallance

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Effects of Chronic Electronic Cigarette Use on Glucose Metabolism, Hannah Hoskinson

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Cardiac and Mitochondrial Dysfunction during Diabetes Mellitus: Examination of Mitochondrial Import Mechanisms, Danielle Lee Shepherd

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The NAD+-Dependent Histone Deacetylase Sirtuin-2 is Upregulated during Myogenesis and Promotes the Differentiation of C2C12 Myoblasts, David A. Stanton

Theses/Dissertations from 2016

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Interleukin-15 Overexpression Attenuates Muscle Fatigue Associated with Murine EO771 Mammary Tumors, Joseph F. Bohlen

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Voluntary Wheel Running Improves Recovery from Muscle Disuse in Mice, Matthew J. Brooks

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Cerebrovascular Dysfunction in Metabolic Syndrome and Depression: Mechanisms and Implications for Neurovascular Disease, Steven David Brooks

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From association to function: elucidating the role of G Protein Signaling Modulator 3 and variants in its gene locus in rheumatoid arthritis, Bryan Jeffery Gall

Theses/Dissertations from 2015

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Do humans drive spinal cord with limb velocity signal?, Kyla Galbreath

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The Effect of a Community-Based Multi-Lifestyle Intervention on Cardiovascular Health in Rural Populations: A Community-Based Participatory Research Approach, Kyuwan Lee

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Cerium dioxide nanoparticle exposure and microvascular dysfunction: Potential mechanistic links, Valerie C. Minarchick

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Chronic Stress, Depressive Symptoms and Peripheral Vascular Dysfunction: Fundamentals, Mechanisms, Sex Disparities, and Determinants of Integrated Outcomes, Shyla Christine Stanley

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Type 1 Diabetic Heart: Examination of Mitochondrial Structure and MicroRNAs, Dharendra Thapa

Theses/Dissertations from 2014

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Inhibition of arterial KDR channels by DPO-1 and activation of cloned human BK channels by BPA-MS, Ibra S. Fancher IV

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Functional characterization of Phosphodiesterase-4A in behavior and obesity, Rolf T. Hansen III

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Roles of nitric oxide and shear stress in the regulation of microvessel permeability in intact rat mesenteric venules, Sulei Xu

Theses/Dissertations from 2013

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Thrombospondin: An emerging keystone in skeletal muscle structure and function, Gerald Nelson Audet

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Effects of estrogen in an aged animal model of stroke, Rachel L. Leon

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The Role of Neurokinin B in the Regulation of the Preovulatory LH Surge in Ewes, Katrina L. Porter

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Lessons in Modeling, Preventing, and Treating Neural Injury: Improving Bench-to- Bedside Translation, Ryan Coddington Turner

Theses/Dissertations from 2012

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Bisphenol A alters the function and expression of BK channels in vascular smooth muscle through membrane and nuclear signals, Shinichi Asano

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The Role of Clustered Organization and Generation of Mixed Properties in Macaque V2, Clinton Garret Cooper

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Modulation of cardiac pacemaker channels by tyrosine phosphorylation, Jianying Huang

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C-peptide Improves Hyperglycemia-induced Endothelial Redox Balance by Preventing Mitochondrial Oxidative Stress and Enhancing NADPH Synthesis, Himani Vejandla

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Roles of eNOS and Nitric Oxide in the Regulation of Microvessel Permeability in Intact Rat Mesenteric Venules, Xueping Zhou

Theses/Dissertations from 2011

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Characterization of the pharmacological effects of digitoxin on lung epithelial cells, Hosam Abdelmonaim Elbaz

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Encoding of Temporal Sound Features in the Rodent Superior Paraolivary Nucleus, Richard A. Felix II

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Vascular Consequences of Metabolic Syndrome Related Shifts in Cyclooxygenase Mediated Arachidonic Acid Metabolism, Adam G. Goodwill

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Molecular Mechanisms of Chromium (VI) - Induced Toxicity and Carcinogenesis, Djordje Medan

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Effects of Age and Early Life Ozone Exposure on the Developmental Dynamics of Afferent Airway Neurons in Postnatal Rats, Leor C. Zellner

Theses/Dissertations from 2010

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Mitochondrial dysfunction in the diabetic heart: Cardioprotection from a novel mitochondrially-targeted therapeutic, Erinne Rose Dabkowski

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Dietary cholesterol effects on learning, memory and amyloid beta: Learning and memory effects on brain cholesterol and sulfatide levels, Deya S. Darwish

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Systemic lipopolysaccharide stimulates airway transepithelial Na+ transport by increasing ENaC and Na+,K+ -pump activity, Michael W. Dodrill

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The Effects of Resveratrol on Oxidative Stress and Muscle Atrophy, Janna Renee Jackson

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The role of nonmuscle Myosin IIA in endothelial cell, Jing Zhu

Theses/Dissertations from 2009

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Role of endothelin 1 in follicular and luteal function in the sheep, Fernando P. Perea-Ganchou

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Effects of aging and exercise training on eNOS uncoupling and reactive oxygen species signaling in the endothelium of skeletal muscle arterioles, Amy L. Sindler

Theses/Dissertations from 2008

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Computer modeling of dapsone-mediated heteroactivation of flurbiprofen metabolism by CYP2C9, Robyn Renee Ayscue

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Caveolin-1 recruitment to the trailing edge of motile cells results in focal adhesion disassembly and nascent interaction with actin stress fibers, Andrew Beardsley

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Putative role of palmitate and Akt signaling in attenuating skeletal muscle growth in the obese zucker rat, Jonathan Michael Peterson

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In vitro elucidation of the metabolic fate of the anticancer drug busulfan, Islam Rasem Younis

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Association of changes in norepinephrine and serotonin transporter expression with the long-term behavioral effects of antidepressant drugs, Zaorui Zhao

Theses/Dissertations from 2007

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Molecular mechanisms of chromium(VI)-induced apoptosis and malignant transformation, Neelam Azad

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Epithelial mechanisms in airway responses induced by hyperosmolarity, Yi Jing

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Expression profiling of oocyte specific genes, transcription factors and microRNAs during early embryonic development in rainbow trout (Onchorhyncus mykiss), Raghuveer K. Ramachandra

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Effects of ovulation of aged follicles, pregnancy diagnosis by ultrasonography, and treatments during lactation on reproduction in ewes, Aimee Kathryn Wurst

Theses/Dissertations from 2006

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Clinically relevant and economic outcomes of maintenance pharmacotherapy in chronic obstructive pulmonary disease (COPD), Anna O. D'Souza

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Modulation of gene expression and DNA adduct formation by chlorophyllin in human mammary cells exposed to benzopyrenes, Kaarthik John

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Esterase inhibition by grapefruit juice and its components leads to newly identified drug interactions, Ping Li

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Oxidative stress in skin induced by chemical and physical agents, Ashley Rebecca Murray

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The extrinsic apoptotic pathway in aged skeletal muscle: Roles of tumor necrosis factor-alpha and interleukin-15, Emidio E. Pistilli

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Effects of environmental factors on the paternal brood pouch and sound production in two sympatric pipefish species from the Chincoteague Bay, Virginia, Jennifer L. Ripley

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Soluble metals of residual oil fly ash alter pulmonary host defense in rats, Jenny Renee Roberts

Theses/Dissertations from 2005

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fMRI studies of amblyopia: Pediatric and adult perspectives, Ian Patrick Conner

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Glutathione conjugation of a cocaine pyrolysis product AEME and related compounds, Alan Lewis Myers

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Cellular mechanisms of luteal regression in the bovine corpus luteum (CL), Aritro Sen

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The effect and mechanism of action of volatile fatty acids on the catabolism of progesterone, Darron Louis Smith

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Factors affecting reproductive efficiency of cattle, Melanie J. Starbuck

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Functional evaluation of cytochrome P450 2D6 allelic isoforms, Weiyan Zhang

Theses/Dissertations from 2004

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Psychophysical studies of binocular and spatial vision in humans with anisometropic and strabismic amblyopia, Ritwick Agrawal

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Interaction between primary alveolar macrophages and primary alveolar type II cells under basal conditions and after lipopolysaccharide or quartz exposure, Rania S. Kanj

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Mechanism of action of NSC3852, a breast cancer differentiation agent, Anna Martirosyan

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Augmentation of the differentiation response to antitumor quinolines, Rayhana Rahim-Bata

Theses/Dissertations from 2003

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On the contribution of MMP-2 and MMP-9 to the postnatal cerebellar corticogenesis, Albert E. Ayoub

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Late embryonic and fetal mortality in the ewe, Alison Brown Dixon

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Metallothionein isoform 3 expression in human bladder urothelium, Seongmi Park

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Cellular specializations for sound localization, Kevin C. Rowland

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Molecular mechanisms of G protein-receptor coupling, Janna Eugenievna Slessareva

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Epileptiform bursting in the disinhibited neonatal cerebral cortex, Jason Eric Wells

Theses/Dissertations from 2002

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Modulation of thiols and pulmonary immune responses due to diesel exhaust particle (DEP) exposure, Nabil Hussain Al-Humadi

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Dendritic development of GABAergic cortical interneurons revealed by biolistic transfection with GFP, Xiaoming Jin

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Anatomical and physiological properties of the superior paraolivary nucleus in the rat, Randy Joseph Kulesza Jr.

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Characterization of metallothionein expression in response to cadmium in the 267-B1, normal prostate cell line, Madhuri G. Neriyanuri

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Antitumor activity of antimalarials in human breast cancer cells, Qun Zhou

Theses/Dissertations from 2001

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Seasonal plasticity of A15 dopaminergic neurons in the ewe, Van Lee Adams

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Prenatal stress alters fear-conditioned behaviors and the response to serotonergic drugs, William C. Griffin III

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Pharmacological regulation of c-myc gene expression in human breast cancer cells, Zaroui Karlen Melkoumian

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Integrated modulation of sympathetic tone in the microcirculation by oxygen, adenosine, and nitric oxide, Bryan Auston Sauls

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Amiodarone-induced pulmonary toxicity in F344 rats, Michael Douglas Taylor

Theses/Dissertations from 2000

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Effects of acetaminophen on estrogen-responsive alkaline phosphatase in Ishikawa endometrial cancer cells, Janet A. Dowdy

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Characterization of the airway epithelial bioelectric mechanisms associated with the effects of epithelium-derived relaxing factor in guinea pig-isolated trachea, Richard Alan Johnston

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Encoding of periodic skin stimuli by spinal dorsal horn neurons, Jeffrey J. Lawson

Theses/Dissertations from 1999

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Androgen-induced norepinephrine release in male accessory sex organ smooth muscle growth and differentiation, Julie M. Kim