Semester

Summer

Date of Graduation

2025

Document Type

Thesis

Degree Type

MS

College

School of Medicine

Committee Chair

Joan Lakoski

Committee Member

Kacie M. Kidd

Committee Member

Amna Umer

Abstract

Intestinal malrotation is a rare condition in which the intestines rotate improperly during embryonic development. Intestinal malrotation is typically diagnosed in pediatric patients with an upper gastrointestinal imaging (UGI) series. Longer time to diagnosis of intestinal malrotation increases the risk of mortality and severe morbidity. While the need for timely diagnosis is well-established in the literature, the correlates of time to diagnosis are largely unknown. The classic medical presentation for intestinal malrotation is an infant presenting with green bilious emesis. I hypothesize that time to diagnosis of intestinal malrotation will be longer in symptomatic pediatric patients when they present differently from the classic presentation (i.e., older pediatric patients not presenting with green bilious emesis) or those who lack access to an UGI due to living in a rural area. This retrospective secondary data analysis project will use the Intestinal Malrotation Outcomes and Wellness Registry (IMPOWER) data to identify factors associated with time to diagnosis of IM from symptom onset in pediatric patients. The rationale for this project is that once the factors associated with time to diagnosis of intestinal malrotation are identified, they can be used to create interventions to reduce time to diagnosis and identify alternative diagnostic screening methods.

Download

Share

COinS