Semester

Summer

Date of Graduation

2002

Document Type

Thesis

Degree Type

MS

College

Davis College of Agriculture, Natural Resources and Design

Department

Animal and Nutritional Sciences

Committee Chair

Hillar Klandorf.

Abstract

Uric acid is an important antioxidant due to its role as a free radical scavenger, and methods to elevate its plasma concentration may be important in animal health. In a preliminary study, the effect of dietary protein on plasma uric acid (PUA) was determined in 3-wk-old chicks. Twenty-four broiler chicks were randomly assigned to 4 diets: low protein (LP) containing 10% casein, medium protein (MP) containing 20% casein, high protein (HP) containing 45% casein and a commercial diet (COD) for 2-wks. PUA concentration increased in chicks fed HP diet and declined in chicks fed LP. In the principal study, PUA and leukocyte oxidative activity (LOA) were also determined. Chicks were fed LP, MP, HP or COD diets for 4 wks. Feed restriction severely restricted body weighs gain in chicks fed synthetic diets. Changes in LOA were found linked to PUA concentrations in chicks fed MP, HP and COD diets.

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