Semester
Spring
Date of Graduation
2011
Document Type
Thesis
Degree Type
MS
College
Eberly College of Arts and Sciences
Department
Chemistry
Committee Chair
Bjorn Soderberg.
Abstract
A one-pot synthesis of substituted dihydrofurans was developed from a Lewis base catalyzed three-component cascade condensation with nitroalkenes, aldehydes and 1,3-dicarbonyl compounds. A large substrate scopes were prepared with excellent diastereoselectivity (trans product only) and excellent yield (up to 95%).
Recommended Citation
Liao, Tao, "Development of Substituted Dihydrofurans and 1,2,3-NH-Triazoles through Lewis Base Catalyzed Cascade Condensation and Their Application in Synthesis of Chiral Triazole Derivatives through Mitsunobu Reaction" (2011). Graduate Theses, Dissertations, and Problem Reports. 3285.
https://researchrepository.wvu.edu/etd/3285