Semester

Summer

Date of Graduation

2021

Document Type

Thesis

Degree Type

MS

College

Davis College of Agriculture, Natural Resources and Design

Department

Animal and Nutritional Sciences

Committee Chair

Scott Bowdridge

Committee Co-Chair

Scott Greiner

Committee Member

Kevin Shaffer

Abstract

Resistance to anthelmintics, more commonly referred to as “de-wormers,” has been on the rise in parasites that affect cattle. Parasite infection can have severe impacts on calf productivity resulting in reduced profitability. Therefore, we sought to better understand anthelmintic resistance in Appalachia by surveying Angus bulls entering performance tests in VA and WV. During a four-year period, over 1050 Angus bulls were tested at bull development facilities in Wardensville, WV, Culpeper, VA and Wytheville, VA. Fecal samples were collected at arrival and 14-21 days later for determination of fecal egg count (FEC) reduction. Upon arrival, all bulls received either fenbendazole (Wardensville, WV) or moxidectin (both VA tests). In Wardensville, treatment with albendazole had a 96.5% FEC reduction, whereas, treatment with moxidectin at Culpeper and Wytheville stations resulted in FEC reduction of 26.3% and 28.6%, respectively. Gain during these 14 days were lower for bulls from Wytheville (0.89 kg/d) than those of Culpeper and Wardensville (1.93 and 2.11 kg/d; respectively). These data can be associated with higher bull FEC after treatment in Wytheville (98.8 eggs/g) compared to bulls in Wardensville and Culpeper (3.3 and 47.8 eggs/g respectively). Additionally, there was a negative correlation between delivery FEC and average daily gain. Taken together these data demonstrate resistance to moxidectin in bulls from the Appalachian region indicating cattle exhibiting these same results will have reduced performance in grazing operations to feedlots and/or for stockers/backgrounders.

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