Amnesia Associated with Bilateral Hippocampal and Bilateral Basal Ganglia Lesions in Anoxia with Stimulant Use

Authors

Marc W. Haut, West Virginia University
Jeffery P. Hogg, West Virginia University
Patrick J. Marshalek, West Virginia University
Blair C. Suter, West Virginia University
Liv E. Miller, West Virginia University

Author ORCID Identifier

https://orcid.org/0000-0003-0235-362X

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Document Type

Article

Publication Date

2017

College/Unit

School of Medicine

Department/Program/Center

Behavioral Medicine and Psychiatry

Abstract

We report a case of a 55-year-old man with ischemic lesions of the bilateral hippocampus and bilateral basal ganglia following a myocardial infarction during an episode of multiple drug use with subsequent anoxia requiring resuscitation. He presented for a neuropsychological evaluation with an anterograde amnesia for both explicit and procedural memory. There are two main points to this case, the unique aspects of the bilateral multifocal lesions and the functional, cognitive impact of these lesions. We hypothesize that his rare focal bilateral lesions of both the hippocampus and basal ganglia are a result of anoxia acting in synergy with his stimulant drug use (cocaine and/or 3,4-methylenedioxy-methamphetamine). Second, his unique lesions produced an explicit and implicit/procedural anterograde amnesia.

Digital Commons Citation

Haut, Marc W.; Hogg, Jeffery P.; Marshalek, Patrick J.; Suter, Blair C.; and Miller, Liv E., "Amnesia Associated with Bilateral Hippocampal and Bilateral Basal Ganglia Lesions in Anoxia with Stimulant Use" (2017). Faculty & Staff Scholarship. 1822.
https://researchrepository.wvu.edu/faculty_publications/1822

Source Citation

Haut, M. W., Hogg, J. P., Marshalek, P. J., Suter, B. C., & Miller, L. E. (2017). Amnesia Associated with Bilateral Hippocampal and Bilateral Basal Ganglia Lesions in Anoxia with Stimulant Use. Frontiers in Neurology, 8. https://doi.org/10.3389/fneur.2017.00027

Comments

© 2017 Haut, Hogg, Marshalek, Suter and Miller. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.