Theses/Dissertations from 2023
ROLE OF CYTOCHROME P450-EPOXYGENASES AND ADENOSINE A2A RECEPTOR IN THE MODULATION OF VASCULAR RESPONSE, Stephanie Onyeka Agba
Right Treatment Wrong Time: Immunotherapy Administration Post-Radiotherapy Decreases Tumor Burden in a Preclinical Model of Brain Metastasis, Kathryn Elizabeth Blethen
CHEMOTHERAPY-INDUCED PDL-1 EXPRESSION IN CANCER-ASSOCIATED FIBROBLASTS PROMOTES CHEMORESISTANCE IN NSCLC, Gayathri Heenatigala Palliyage
Gut-Lung Axis of the Microbiome Alterations After Ultrafine Particles and Ozone Inhalation, Md Habibul Hasan Mazumder
Heat Shock Protein 90 (HSP90) system in health and disease., Daniella Munezero
Specialized metabolism in retina, retinal pigmented epithelium, and testis, Siyan Zhu
Theses/Dissertations from 2022
Exploiting modulation of the Blood-Brain and Blood-Tumor Barrier permeability by Translational Focused Ultrasound for therapeutic delivery to CNS metastases, Tasneem A. Arsiwala
Targeting Vulnerabilities in Cell State and Calcium Signaling for the Treatment of Lung Cancer, Clark Jones
THE EXPOSOME, METABOLIC DYSFUNCTION AND SILICOSIS: A PULMONARY AND PATHOPHYSIOLOGY STUDY, Janet A. Thompson
AGING, A PATHOLOGICAL FACTOR IN NEUROLOGICAL INJURY, ARUVI VIJIKUMAR
Theses/Dissertations from 2021
In vitro and in vivo toxicological evaluation of emissions from the fused filament fabrication three-dimensional printing, Mariana T. Farcas
Understanding the Variable Drivers of Toxicity for the Broad Class of Carbon Nanotubes and Nanofibers from U.S. Facilities, Kelly E. Fraser
Investigation of novel mitoNEET ligand NL-1 as a therapeutic for cerebral ischemia and reperfusion injury, Pushkar Saralkar
From inner segment to outer segment: Palmitoylation of photoreceptor Na+, K+-ATPase and the importance of PRCD in photoreceptor outer segment morphogenesis, Emily R. Sechrest
Bypassing the Blood-Brain Barrier: A Physical and Pharmacological Approach for the Treatment of Metastatic Brain Tumors, Samuel A. Sprowls
Theses/Dissertations from 2020
The Interplay of Progestins, Matrix Metalloproteinases, and the Aging Brain, Keyana Nicole Porter
Theses/Dissertations from 2019
Metal Nanomaterials: Immune Effects and Implications of Physicochemical Properties on Sensitization, Elicitation, and Augmentation of Allergic Disease, Katherine Adair Roach
Theses/Dissertations from 2018
The Role of Interleukin-12 and Exosomes in the Dynamic Interplay of Cancer and the Immune System, Christina Nicole Nikki Byrne-Hoffman
Investigational Chemotherapy and Novel Pharmacokinetics for the Treatment of Cancers of the CNS, Neal Shah
Theses/Dissertations from 2017
Depression, Treatment Response to TNFi, and Economic Outcomes among Working-Age Adults with Rheumatoid Arthritis, Arijita Deb
The Role of Somatostatin in the Regulation of Gonadotropin Secretion in Sheep, Richard B. McCosh
The Dynamics of Economic Status and Health among Working-Age Adults in the United States, Abdulkarim Mohammad Meraya
Novel Treatment Strategies for Brain metastases of Breast Cancer, Afroz Shareef Mohammad
Transitions Within Opioid Therapy and Their Impact on Morbidity, Healthcare Utilization, and Costs, James Douglas Thornton
Theses/Dissertations from 2016
Risk of Newly-diagnosed Depression, Treatment and its Economic Outcomes among Elderly Medicare Beneficiaries with Incident Breast, Colorectal or Prostate Cancer, Monira Mansour Alwhaibi
Distribution and efficacy of chemotherapeutics in the treatment of preclinical brain metastases of breast cancer, Tori Terrell Hall
Modulation of Coronary Reactive Hyperemia through Soluble Epoxide Hydrolase: Role of Oxylipins and PPARgamma, Ahmad Mahmoud Hanif
Elucidating Mechanisms of Neurobehavioral Dysfunction in a Rodent Model of Traumatic Brain Injury, Aric F. Logsdon
Effects of Pristine and Nitrogen-Doped Multi-Walled Carbon Nanotubes on Human Lung Epithelial and Fibroblast Cells, Amy Mihalchik
Targeting the Peripheral Immune System as a Source of Precision Stroke Biomarkers: Implications for Clinical Diagnostics and Immunotherapeutics, Grant C. O'Connell
Autism Spectrum Disorders among Adults: Burden of Healthcare Services' Utilization and Expenditures, Rini Vohra
Theses/Dissertations from 2015
Longitudinal Patterns and Economic Consequences of Emergency Department Visits among Medicaid Enrollees, Parul Agarwal
Types of Co-existing Chronic Physical Conditions and Newly-diagnosed Depression, its Treatment and Economic Outcomes among Medicaid Beneficiaries with Type 2 Diabetes, Rituparna Bhattacharya
Use of protein immobilization to measure cytochrome P450 conduction and metabolism kinetics, Christopher D. Bostick
Metal Oxide Nanoparticles: The Importance of Size, Shape, Chemical Composition, and Valence State in Determining Toxicity, Katherine Dunnick
Analytical and Computational Methods for the Assessment of Biological Molecules and their Binding Interactions: Case Studies in DNA Aptamer-Target Binding and P450-P450 Dimerization, Katherine M. Hickey
Identification and Biosensing Application of Molecular Recognition Elements, Ka Lok Hong
Role of Stem-like Cells in Carbon Nanotube-Induced Pulmonary Fibrosis, Amruta Manke
Evaluation of the antidepressant potential of dextromethorphan, Linda Nguyen
Impact of Chronic Conditions on Treatment, Cancer-and Non-Cancer Outcomes among Elderly Men with Incident Prostate Cancer, Amitkumar Dineshchandra Raval
Theses/Dissertations from 2014
Multimorbidity, Management of COPD and Health Outcomes among Medicaid Beneficiaries, Mayank Ajmera
Understanding the Mechanism of Hard Metal (WC-Co) Toxicity: In vitro Studies and In vivo Exploration, Andrea Lynn Armstead
Burden of Illness among Elderly Individuals with Parkinson's disease, Sandipan Bhattacharjee
Pharmacological Characterization of Novel Opioid Receptor Ligands Aimed at Reducing the Development of Tolerance, Jason Randall Healy
High salt diet-induced alteration in vascular reactivity in wild-type and adenosine A2A receptor null mice, Isha Pradhan
Burden of Colorectal Cancer among the elderly Medicare beneficiaries in West Virginia A comparative analysis with national data, Pallavi Balwant Rane
Nerve growth factor regulates Na+ transport in human airway epithelial cells, Michael J. Shimko
C8-Arylguanine Modified Hairpin Oligonucleotides: Synthesis, Conformational Analysis, and Tools for the Investigation of Z-DNA Formation, Brian C. Train
Burden of Breast Cancer and Associated Health and Economic Outcomes in Elderly Women in West Virginia: Comparison with National Estimates, Ami Maulik Vyas
Effects of the popcorn flavorings, diacetyl and 2,3-pentanedione, in the airways, Eric J. Zaccone
Theses/Dissertations from 2013
Involvement of CytochromeP4504a in Adenosine A1 receptor mediated regulation of vascular tone, Swati S Kunduri
The Involvement of Sigma Receptor Modulation in the Antidepressant Effects of Ketamine and the Neurotoxic Actions of Methamphetamine, Matthew J. Robson
Investigations in Molecular Recognition Element Selection and Single-Wall Carbon Nanotube Properties, Ryan Martin Williams
Theses/Dissertations from 2012
Patient Preferences for Benefits and Risks Associated with Disease Modifying Drugs in Multiple Sclerosis, Abhijeet J. Bhanegaonkar
Infection Models of Intracellular Staphylococcus aureus and The Impact of Interleukin 12 on Macrophage Killing Activity, Therwa Hamza
Evaluation of novel sigma receptor antagonists against METH-induced neurotoxicity: in vivo and in vitro studies, Nidhi Kaushal
Pharmacological Characterization of Sigma-2 Preferring Compounds: Implications in Cocaine-induced Behaviors, Bahar Noorbakhsh
Pharmacological Characterization of an Optimized Sigma Receptor Ligand, Michael Seminerio
Theses/Dissertations from 2011
New methodologies for in vitro analysis of binding and functional activity of sigma receptor ligands, James A. Fishback
Role and Contribution of A2 Adenosine Receptors in the Regulation of Coronary Flow, Maryam Sharifi Sanjani
Immobilized Cytochrome P450 2C9 (CYP2C9): Applications for Metabolite Generation, Monitoring Protein-Protein Interactions, and Improving In-vivo Predictions Using Enhanced In-vitro Models, Lance A. Wollenberg
Phosphodiesterase-4 in the Brain: Effects of Pharmacological Inhibition and Mutation of DISC1, Lan Xiao
Theses/Dissertations from 2010
Assessing the Influence of Coronary Heart Disease Knowledge, Perception of Personal Risk, and Delay Discounting of Future Health on Diet and Physical Activity, Kimberly Bosworth Blake
Cytochrome P450 1A-ligand interactions: Implications for substrate specificity and inhibitor susceptibility, Qingbiao Huang
Theses/Dissertations from 2009
The role of NADPH oxidase in blood -brain barrier dysfunction following stroke in aged rats, Kimberly Kelly
Properties of a dehydroalanine analog of glutathione: A reactive electrophilic busulfan metabolite, Cody J. Peer
Examining the protective effects of sesamol on oxidative stress associated blood -brain barrier dysfunction in streptozotocin-induced diabetic rats, Reyna VanGilder
The effect of C8-arylguanine adducts on B/Z-DNA equilibrium: Implications in aryl hydrazine carcinogenesis, Vorasit Vongsutilers
Theses/Dissertations from 2008
Involvement of adenosine A1 receptors in systemic inflammation and altered vascular reactivity in allergic mice, Dovenia S. Ponnoth
Theses/Dissertations from 2007
Effects of the common pesticide methoxychlor on ovarian steroidogenesis, Yucel Akgul
Effect of diesel exhaust particles on allergic reactions and airway responsiveness in ovalbumin-sensitized brown Norway rats, Caroline Dong
Theses/Dissertations from 2006
IQGAP1 knockdown enhances the endothelial barrier in vitro, Wentao Zhang
Theses/Dissertations from 2005
Assessing the cost-effectiveness of tumor necrosis factor inhibitors and prescribing practices of rheumatologists in patients with rheumatoid arthritis, Khalid M. Kamal
Pharmaceutical performance testing of commercially available calcium supplements, Jianqing Liu
Economic evaluation of prophylactic antiemetic regimens for prevention of chemotherapy -induced nausea and vomiting (CINV), Reema R. Mody
Quality of life and clinical outcomes in Type 2 diabetes patients at the primary care clinics of the West Virginia University Hospital, Murali Sundaram
Mass spectrometry of metallothionein adducts as candidate biomarkers of styrene oxide and 1-phenylpropylene oxide, Sandra G. Tarr
Theses/Dissertations from 2004
Characterization of CYP2D protein from human brain cerebellum, Deepak Bhatia
Epidemiological burden of depression and its impact on adherence to oral hypoglycemic agents and related economic outcomes in patients with type 2 diabetes, Iftekhar D. Kalsekar
Evaluation of novel cross -linking agents for gelatin/collagen matrices, Brenda J. Schuler
Theses/Dissertations from 2003
Economics of breast cancer preventive strategies in a Medicaid program, Rohit D. Borker
Evaluating utilization of beta -blockers as secondary prevention for post myocardial infarction in a Medicaid population, Ancilla W. Fernandes
Dapsone activation of CYP2C9 allelic variants, Matthew Aaron Hummel
Regulation of P-glycoprotein and ABCP transporters, Dhanashri Ramkrishna Kolwankar
Uterine uptake of diazepam and quantification by gas chromatography/mass spectrometry, Steven Scott Wolfe
Pharmaceutical quality performance of folic acid supplements, Islam Rasem Younis
Theses/Dissertations from 2002
Theses/Dissertations from 2001
Factors affecting CYP2C9-mediated metabolism, James Matthew Hutzler
Transport and utilization of arginine and arginine-containing peptides by rat alveolar macrophages, Xiaodong Yang
Theses/Dissertations from 2000
West Virginians' perceptions and use of complementary medicine, Joshua David Blevins
IL -10 gene therapy for the treatment of pulmonary inflammation, Sujatha Dokka
Theses/Dissertations from 1999
Evaluation of non-invasive biomarkers for carcinogenic exposure to cigarette smoke, Girish Srinivas Gudi