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Theses/Dissertations from 2024

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Studies in Nonlinear Chemical Dynamics of Propagating Precipitation Waves, Md Boshir Ahmed

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Room Temperature Decarboxylative Amination Reactions of Carboxylic Acids, Rabina Basnet

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Investigation of Deoxyfluorination of Alkyl Alcohols Using Pentafluoropyridines through a Covalent Intermediate, Christopher Allen Bias

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Photoinduced alpha-Hydroxy C–H Alkylation of Mono-alcohols via Hydrogen Atom Transfer (HAT) of an Activated Boron-Containing Complex, Courtney Deanna Glenn

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Additive-Dependent Regioselective Boracarboxylation of Alkenes using Low Valent Copper and CO2, Carly H. Gordon Ph.D.

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Experimental and Chemical Modeling of Applied DC Electric Field Induced H2 – Air Axisymmetric Laminar Co-Flow Diffusion Flames with Low Carbon Impurities, Susith Dilshan Pathmasiri Gunamuni Halowitage

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Synthetic Elaboration of β-Carbonyl Alkylboronic Esters, Mason D. Hamilton Ph.D.

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Development of Lab-on-a-Chip platforms incorporating a novel Acoustic atomization induced pump based on a vibrating sharp edge capillary., Balapuwaduge Lihini Tharanga Catherine Mendis

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S(+)-Propylnorapomorphine Hydrochloride Alters Mutant Huntingtin Aggregation and Membrane Interactions, Gabriella M. Pettipas

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C–H Alkylation of Diol Substrates using Bifunctional Boronic Acid Catalysts, Matthew Ryan Ross

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Kinetic Study of OH Radical Reactions with Cyclopentenone Derivatives, Patrick Kipkoech Rutto

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Spiral Wave Teleportation and Multiplex Network Synchronization in Light Sensitive Belousov-Zhabotinsky Systems, Shannyn Alicia Tyler

Theses/Dissertations from 2023

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Application of computational biophysics techniques to characterize cell membrane-associated events, Kyle Billings

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Solid State NMR Analysis of Insect Wing Membranes, Samuel Eddy

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SYNTHESIS AND PHARMACOLOGY OF ILLUDALIC ACID AND ANALOGOUS CHEMICAL STRUCTURES, Robert Gaston Jr

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Exploration of Metal-Carbonyl Complexes for Decarbonylation Reactions, Rebekah C. Krupa

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Investigations into Indole Formation: Base-mediated Formation of N-hydroxy- and N-alkoxyindoles, Ancillary Ligand Development for Watanabe-Cenini-Söderberg Cyclization, and Total Synthesis of Racemosin B, Blaine Thomas McClay

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Investigating the interactions of the iron-sulfur mitochondrial protein, mitoNEET with its binding partners, Ebenezer Osei Newton

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Enantioselective Dearomatization Facilitated by Non-Covalent Interactions of N-Heterocyclic Carbene Catalysts and Pyridinium Salts, Jack A. Patterson

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Developing new ionization strategies for characterizing structural flexibility, heterogeneity, and transformation of biopolymers, Daud Sharif

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Lipid binding properties of huntingtin as a novel therapeutic target, Chathuranga Siriwardhana

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Exogenous factors that impact huntingtin aggregation, Adam Skeens

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Copper-Catalyzed Dehydrogenative Decarboxylation Reactions of Carboxylic Acids to Alkenes, Michael P. Stanton

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Investigation of Early Complex Formation of Huntingtin Protein With and Without Lipids, Alyssa R. Stonebraker

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Enabling Technologies for Chemical Synthesis: I. Selective Microwave Heating; II. Synthesis and Regioselective Cyclotrimerizations of Tethered 1,6-Diynes, Amir Tavakoli

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Development of Novel Mass Spectrometry Method for the Analysis of Complex Compounds, jing wang

Theses/Dissertations from 2022

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Multifunctional Organoboron Compounds and Boralactonate Salts, Randika T. Abeysinghe

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The Use of Neural Networks in Accelerating Small Molecule Docking of GPCRs, John Barber

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Advancing Compound Detection and Identification Using Vibrating Sharp-Edge Spray Ionization, Anthony Paul DeBastiani

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Photophysics and Photochemistry Enabled by Ligand-to-Metal-Charge-Transfer: Unusual Carbon-Carbon Bond Formation at a Zirconium Center, P. Minh N. Do

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Enhanced Sampling Techniques Reveal Key Information about Membrane Active Peptides, Nicolas Charles Frazee

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Characterizing the Effects of Solvent and Analyte Properties on Ionization Efficiency by Novel Field-free and Field-enabled Ionization Techniques, Kinkini Udara Jayasundara

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Synthetic Methods for Improved Scope and Efficiency of Copper-Catalyzed Regioselective Alkene Boracarboxylation, Steven William Knowlden

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Electronic Structure of Early Transition Metal Complexes Supported by Pyridine Polypyrrolide Ligands, Dylan Connor Leary

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Study of Resonantly Stabilized Radicals in Combustion Environments, James H. Lee

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Development of Capillary Vibrating Sharp-Edge Spray Ionization for Improving Continuous Flow Mass Spectrometry Analysis, Chong Li

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Synthesis and Cyclotrimerization of Sulfonyl Enynes, Alexa C. Martin

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SYNTHESIS, CHARACTERIZATION, AND ACTIVATION OF PYRIDINE DIPYRROLIDE SUPPORTED VANADIUM-NITROGEN MULTIPLE BONDS, Jordan Cruz Martinez

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Heterogeneous oxidation of multi-component aqueous organic aerosols: The effect of transport phenomena and reaction compartment on reaction kinetics., Tadini wenyika Masaya

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Novel Modes of Synchronization and Extreme Events in Coupled Chemical Oscillators, David Allen Mersing

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Tandem Addition/Fragmentation Reactions of Vinylogous Acyl Sulfonates, Kristen S. Nerbecki

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Syntheses of indoles and natural indole alkaloids from 2-nitrostyrene derivatives, S M Ashikur Rahman

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Capillary Electrophoresis: Method Development and Application in Biomolecule Analysis, Lindsay Marie Veltri

Theses/Dissertations from 2021

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Huntingtin aggregation at interfaces associated with membranes and organelles, Adewale Vincent Adegbuyiro

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Enhancing Negative-Ion Native Mass Spectrometry with Field-Assisted Capillary Vibrating Sharp-Edge Spray Ionization (cVSSI), Kushani Udeshika Attanayake

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Understanding the relationship between local environmental changes and the function of the pH Low Insertion Peptide, Violetta Burns Casamayor

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Employing Exoglycosidase And Transferase Enzymes in Capillary Nanogel Electrophoresis for the Determination of N-glycan Linkages and Enzyme Michaelis-Menten Constants., Lloyd Bwanali

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Gas Phase Reactions of Cyclopentadiene with CH and OH Radicals, Kacee Lynn Caster

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Unique Biological Applications of Charge Transfer Dissociation Mass Spectrometry, Halle M. Edwards

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Modified Firearm Discharge Residue Analysis utilizing Advanced Analytical Techniques, Complexing Agents, and Quantum Chemical Calculations, William J. Feeney

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Enabling Technologies for Medicinal Chemistry and Synthesis: I. Cannabinoids; II. Illudalic Acid; III. Microwave Chemistry, Harvey Fulo

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Harnessing Acoustic Streaming for Bioanalysis in Microfluidics, Xiaojun Li

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Improving Characterization of Small Molecules using Enhanced Molecular Reaction and Ionization Techniques, Sandra N. Majuta

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Online Ultra-High Performance Liquid Chromatography-Charge Transfer Dissociation-Mass Spectrometry (UHPLC-CTD-MS) of Complex Mixtures of Oligosaccharides, Praneeth M. Mendis

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Exploring early signaling associated with complex stressors, Julia A. Penatzer

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Analysis of Cell Signaling Perturbations in Response to Chronic Localized Infections, Amber Nicole Prince

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Design and Synthesis of Targeted Immunotherapeutic Agents, Md Shohel Rana

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Development of Vibrating Sharp-edge Spray Ionization (VSSI) methods for Mass Spectrometry Analysis and Imaging, Nandhini Ranganathan

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Fundamentals and Applications of Charge Transfer Dissociation Mass Spectrometry, Zachary Joseph Sasiene

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Using Molecular Dynamics to Characterize the Relationship between Membrane Components and Dynamics and Supramolecular Organization of Membrane Proteins, Eric Sefah

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Photochemical Motion Control of Belousov-Zhabotinsky Droplets and Turbulence-like Patterns in the Aluminum Hydroxide Precipitation System, Syed Jazli Syed Jamaluddin

Theses/Dissertations from 2020

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Development of New Synthetic Methods for Carbon Nanohoops, Merfat Aljhdli

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Mechanistic Analysis of Reductive Boracarboxylation Using Low Valent Copper and CO2, Notashia Nicole Baughman

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The effects of membrane physicochemical properties on huntingtin membrane association and downstream aggregation, Maryssa Beasley

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Capillary Electrophoresis Analysis of Proteins using Phospholipid Based Materials, Cassandra L. Crihfield

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Silver-Mediated Decarboxylation Reactions: Expanding Reaction Scope through Kinetic Analysis, Robert Anthony Crovak

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Factors Influencing Huntingtin Aggregation at Surfaces: Implications for Huntington’s Disease, Sharon E. Groover

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Synthesis and Characterization of Pyridine Dipyrrolide Iron Complexes Relevant to Nitrene and Carbene Group Transfer, Brett M. Hakey

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Protein/peptide characterization using mass spectrometry and molecular dynamics simulations, Ahmad Kiani Karanji

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Development and implementation of a novel voltage-free interface for capillary electrophoresis-mass spectrometry separations of proteins, Courtney J. Kristoff

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Cobalt-Catalyzed Aerobic Oxidative Cyclization Reactions of Bisnucleophiles: New Methodologies and the Role of Bisnucleophiles in O2 Activation, Jiaqi Liu

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Targeting the Nt17 of the huntingtin protein via natural and chemical modifications: impact on aggregation and membrane interactions, Faezeh Sedighi

Theses/Dissertations from 2019

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Experimental and modeling investigation of the OH-initiated oxidation of semi-solid and aqueous saccharide aerosols, hanyu fan

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Non-target Analyses of Novel Psychoactive Substances; Inherent Variation in GCMS Relative Abundances and Gas Phase Hydrogen Deuterium Exchange Isomer Discrimination, Kristin Michelle Kelly

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Copper-Catalyzed Regioselective Boracarboxylation of Vinyl Arenes: Catalytic Efficiency and Synthetic Utility, Trina M. Perrone

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The impact of post translational modification on the aggregation of the ß-amyloid peptide in the presence or absence of lipids, Albert Walton Pilkington IV

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In Situ Infrared Spectroscopic Study of Iron-Catalyzed Hydromagnesiation of Vinyl Arenes, Jessica Ann Rogers

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Photoluminescent Zirconium Complexes for Visible Light Photoredox Catalysis, Yu Zhang

Theses/Dissertations from 2018

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Molecular Dynamics and Nonlinear Dynamics Studies of Chemical Systems, Sadegh Faramarzi Ganj Abad

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Electrophoretic Characterization of Carbon Nanotubes: Elucidation of Surface Functionalization and Interaction, Tyler A. Davis

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Integrating Microscale Enzyme And Lectin Reactions Using Nanogel Assisted Capillary Electrophoresis, Srikanth Gattu

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Syntheses of azepinoindole alkaloids cimitrypazepine, fargesine and hyrtioreticulins C & D, Ganesh Ghimire

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Biophysical Investigation of pHLIP-Membrane Interaction, Chitrak Gupta

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Nickel-Catalyzed Oxidative Decarboxylative (Hetero)Arylation Reactions, Aaron P. Honeycutt

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Base-mediated formation of N-hydroxy- and N-alkoxyindoles, synthesis of dilemmaones A and B, and novel efforts in indole methodology and total synthesis, Katharine Elizabeth Lambson

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Syntheses and Structures of Functionalized Carbon Nanohoops, Shuangjiang Li

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Late-Transition Metal Complexes with Ambiphilic Phosphinoborane Ligands: Synthesis, Characterization and Catalysis., Brian R. Nichols

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The Determination and Evaluation of Pyrolytic Products: A Focus on Synthetic Cannabinoids, Stephen Raso

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Syntheses and Properties of Thiophene-containing Cycloparaphenylenes and Related Macrocycles and a Strained Cyclophane, Haresh Thakellapalli

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The Electrochemistry of Metal Carbides: From Salt Melt Synthesis to Voltammetry of Microparticles, Rachel Lee Tani Walker

Theses/Dissertations from 2017

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Synthesis of indoles, biindoles, indole alkaloids, pyrroloindoles and benzimidazoles from aromatic nitro compounds and a study of the chemoselectivity in the Kosugi-Migita-Stille coupling, Nurul Hoda Ansari

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Syntheses of Functionalized Cycloparaphenylenes, Furan-Containing Cycloparaphenylenes, and Related Thiophene-Containing Fused Carbon Nanohoop, Behzad Farajidizaji

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Gas-Phase Protein Structure Characterization with Ion Mobility Mass Spectrometry and Molecular Dynamics Simulations, Samaneh Ghassabi Kondalaji

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Investigating stress response across integrated biological systems, Alice A. Han

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Provenance of the Hamilton Group: A Study of Source-to-Sink Relationships within the Middle Devonian Central Appalachian Basin, Brittany N. Hupp

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A Study of Solid Oxide Fuel Cell Materials at High Temperature Using an Environmental Scanning Electron Microscope, Mahfuzur Rahman Jony

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Protein and Peptide Gas-phase Structure Investigation Using Collision Cross Section Measurements and Hydrogen Deuterium Exchange, Mahdiar Khakinejad

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Charge Transfer Dissociation Mass Spectrometry of Biomolecules, Pengfei Li

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Complex Mixture Analysis Using Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS) and Computational Techniques, Hossein Maleki

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Proteomic and Metabolomic Analyses of Biological Systems with Liquid Chromatography Tandem Mass Spectrometry and Ion Mobility Mass Spectrometry, Megan M. Maurer