Semester

Spring

Date of Graduation

1999

Document Type

Thesis

Degree Type

MS

College

School of Pharmacy

Department

Pharmaceutical Systems and Policy

Committee Chair

David Nau

Committee Co-Chair

Sidney Rosenbluth.

Abstract

Purpose. To investigate the relationship of disease severity, health beliefs, and medication adherence among HIV/AIDS patients.;Results. Seventy-two HIV patients were enrolled. There were no significant differences in patients' perceived severity of HIV/AIDS and perceptions of benefits and barriers of the treatment across three disease stages. However, patients who had greater experience with the disease (stage C) perceived a higher risk to develop complications if they were not adherent compared to asymptomatic patients (stage A). Results also revealed that patients in stage B and C were more adherent to their medications compared to patients in stage A when regimen complexity was controlled. Finally, perceived susceptibility-inaction was positively related to medication adherence and difficulty in following doctors' instructions was negatively related to adherence.;Implications. Patients' medication taking behaviors can be improved by targeting issues specific to the individual patient and helping patients understand the negative consequences of poor adherence.

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