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Theses/Dissertations from 2021

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In vitro and in vivo toxicological evaluation of emissions from the fused filament fabrication three-dimensional printing, Mariana T. Farcas

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Understanding the Variable Drivers of Toxicity for the Broad Class of Carbon Nanotubes and Nanofibers from U.S. Facilities, Kelly E. Fraser

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Investigation of novel mitoNEET ligand NL-1 as a therapeutic for cerebral ischemia and reperfusion injury, Pushkar Saralkar

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From inner segment to outer segment: Palmitoylation of photoreceptor Na+, K+-ATPase and the importance of PRCD in photoreceptor outer segment morphogenesis, Emily R. Sechrest

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Bypassing the Blood-Brain Barrier: A Physical and Pharmacological Approach for the Treatment of Metastatic Brain Tumors, Samuel A. Sprowls

Theses/Dissertations from 2020

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The Interplay of Progestins, Matrix Metalloproteinases, and the Aging Brain, Keyana Nicole Porter

Theses/Dissertations from 2019

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Critical Physicochemical Properties for Nanoparticle Toxicity: Impact of Surface Coating and Size on Particle-Induced Cell Transformation and Inflammatory Response, Tiffany Kornberg

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Metal Nanomaterials: Immune Effects and Implications of Physicochemical Properties on Sensitization, Elicitation, and Augmentation of Allergic Disease, Katherine Adair Roach

Theses/Dissertations from 2018

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The Role of Interleukin-12 and Exosomes in the Dynamic Interplay of Cancer and the Immune System, Christina Nicole Nikki Byrne-Hoffman

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Switching from Vitamin K Antagonists to Non-vitamin K Oral Anticoagulants, Drug-Drug Interactions, and Health Outcomes among Working-Age Adults with Atrial Fibrillation, Xue Feng

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Investigational Chemotherapy and Novel Pharmacokinetics for the Treatment of Cancers of the CNS, Neal Shah

Theses/Dissertations from 2017

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Impact of Incident Cancer on Coronary Artery Disease-Related Concomitant Medication Adherence, Short-Term Health and Economic Outcomes Among Elderly Medicare Beneficiaries with Coronary Artery Diseas, Ishveen Kaur Chopra

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Depression, Treatment Response to TNFi, and Economic Outcomes among Working-Age Adults with Rheumatoid Arthritis, Arijita Deb

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The Impact of Diffuse Large B-Cell Lymphoma on Primary Care and Costs of Chronic Conditions in Elderly Medicare Beneficiaries, Rahul Garg

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The Role of Somatostatin in the Regulation of Gonadotropin Secretion in Sheep, Richard B. McCosh

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The Dynamics of Economic Status and Health among Working-Age Adults in the United States, Abdulkarim Mohammad Meraya

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Novel Treatment Strategies for Brain metastases of Breast Cancer, Afroz Shareef Mohammad

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Transitions Within Opioid Therapy and Their Impact on Morbidity, Healthcare Utilization, and Costs, James Douglas Thornton

Theses/Dissertations from 2016

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Risk of Newly-diagnosed Depression, Treatment and its Economic Outcomes among Elderly Medicare Beneficiaries with Incident Breast, Colorectal or Prostate Cancer, Monira Mansour Alwhaibi

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Distribution and efficacy of chemotherapeutics in the treatment of preclinical brain metastases of breast cancer, Tori Terrell Hall

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Modulation of Coronary Reactive Hyperemia through Soluble Epoxide Hydrolase: Role of Oxylipins and PPARgamma, Ahmad Mahmoud Hanif

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Assessment of molecular action of direct gating and allosteric modulatory effects of meprobamate (MiltownRTM) on GABA A receptors, Manish Kumar

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Elucidating Mechanisms of Neurobehavioral Dysfunction in a Rodent Model of Traumatic Brain Injury, Aric F. Logsdon

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Effects of Pristine and Nitrogen-Doped Multi-Walled Carbon Nanotubes on Human Lung Epithelial and Fibroblast Cells, Amy Mihalchik

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Targeting the Peripheral Immune System as a Source of Precision Stroke Biomarkers: Implications for Clinical Diagnostics and Immunotherapeutics, Grant C. O'Connell

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Autism Spectrum Disorders among Adults: Burden of Healthcare Services' Utilization and Expenditures, Rini Vohra

Theses/Dissertations from 2015

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Longitudinal Patterns and Economic Consequences of Emergency Department Visits among Medicaid Enrollees, Parul Agarwal

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Types of Co-existing Chronic Physical Conditions and Newly-diagnosed Depression, its Treatment and Economic Outcomes among Medicaid Beneficiaries with Type 2 Diabetes, Rituparna Bhattacharya

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Use of protein immobilization to measure cytochrome P450 conduction and metabolism kinetics, Christopher D. Bostick

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Metal Oxide Nanoparticles: The Importance of Size, Shape, Chemical Composition, and Valence State in Determining Toxicity, Katherine Dunnick

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Analytical and Computational Methods for the Assessment of Biological Molecules and their Binding Interactions: Case Studies in DNA Aptamer-Target Binding and P450-P450 Dimerization, Katherine M. Hickey

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Identification and Biosensing Application of Molecular Recognition Elements, Ka Lok Hong

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Assessment of molecular action of direct gating and allosteric modulatory effects of carisoprodol (SomaRTM) on GABA A receptors, Manoj Kumar

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An Analysis of Treatment Patterns, Receipt of Guideline-Concordant Care, and Survival Outcomes among Elderly Women with Non-Metastatic Breast Cancer Using the SEER-Medicare Linked Dataset, Traci LeMasters

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Role of Stem-like Cells in Carbon Nanotube-Induced Pulmonary Fibrosis, Amruta Manke

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Evaluation of the antidepressant potential of dextromethorphan, Linda Nguyen

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Impact of Chronic Conditions on Treatment, Cancer-and Non-Cancer Outcomes among Elderly Men with Incident Prostate Cancer, Amitkumar Dineshchandra Raval

Theses/Dissertations from 2014

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Multimorbidity, Management of COPD and Health Outcomes among Medicaid Beneficiaries, Mayank Ajmera

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Understanding the Mechanism of Hard Metal (WC-Co) Toxicity: In vitro Studies and In vivo Exploration, Andrea Lynn Armstead

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Burden of Illness among Elderly Individuals with Parkinson's disease, Sandipan Bhattacharjee

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Pharmacological Characterization of Novel Opioid Receptor Ligands Aimed at Reducing the Development of Tolerance, Jason Randall Healy

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High salt diet-induced alteration in vascular reactivity in wild-type and adenosine A2A receptor null mice, Isha Pradhan

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Burden of Colorectal Cancer among the elderly Medicare beneficiaries in West Virginia A comparative analysis with national data, Pallavi Balwant Rane

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Nerve growth factor regulates Na+ transport in human airway epithelial cells, Michael J. Shimko

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C8-Arylguanine Modified Hairpin Oligonucleotides: Synthesis, Conformational Analysis, and Tools for the Investigation of Z-DNA Formation, Brian C. Train

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Burden of Breast Cancer and Associated Health and Economic Outcomes in Elderly Women in West Virginia: Comparison with National Estimates, Ami Maulik Vyas

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Effects of the popcorn flavorings, diacetyl and 2,3-pentanedione, in the airways, Eric J. Zaccone

Theses/Dissertations from 2013

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Involvement of CytochromeP4504a in Adenosine A1 receptor mediated regulation of vascular tone, Swati S Kunduri

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The Involvement of Sigma Receptor Modulation in the Antidepressant Effects of Ketamine and the Neurotoxic Actions of Methamphetamine, Matthew J. Robson

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Investigations in Molecular Recognition Element Selection and Single-Wall Carbon Nanotube Properties, Ryan Martin Williams

Theses/Dissertations from 2012

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Patient Preferences for Benefits and Risks Associated with Disease Modifying Drugs in Multiple Sclerosis, Abhijeet J. Bhanegaonkar

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Infection Models of Intracellular Staphylococcus aureus and The Impact of Interleukin 12 on Macrophage Killing Activity, Therwa Hamza

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Evaluation of novel sigma receptor antagonists against METH-induced neurotoxicity: in vivo and in vitro studies, Nidhi Kaushal

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Pharmacological Characterization of Sigma-2 Preferring Compounds: Implications in Cocaine-induced Behaviors, Bahar Noorbakhsh

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Pharmacological Characterization of an Optimized Sigma Receptor Ligand, Michael Seminerio

Theses/Dissertations from 2011

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New methodologies for in vitro analysis of binding and functional activity of sigma receptor ligands, James A. Fishback

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Role and Contribution of A2 Adenosine Receptors in the Regulation of Coronary Flow, Maryam Sharifi Sanjani

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Immobilized Cytochrome P450 2C9 (CYP2C9): Applications for Metabolite Generation, Monitoring Protein-Protein Interactions, and Improving In-vivo Predictions Using Enhanced In-vitro Models, Lance A. Wollenberg

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Phosphodiesterase-4 in the Brain: Effects of Pharmacological Inhibition and Mutation of DISC1, Lan Xiao

Theses/Dissertations from 2010

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Assessing the Influence of Coronary Heart Disease Knowledge, Perception of Personal Risk, and Delay Discounting of Future Health on Diet and Physical Activity, Kimberly Bosworth Blake

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Cytochrome P450 1A-ligand interactions: Implications for substrate specificity and inhibitor susceptibility, Qingbiao Huang

Theses/Dissertations from 2009

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The role of NADPH oxidase in blood -brain barrier dysfunction following stroke in aged rats, Kimberly Kelly

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Properties of a dehydroalanine analog of glutathione: A reactive electrophilic busulfan metabolite, Cody J. Peer

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Examining the protective effects of sesamol on oxidative stress associated blood -brain barrier dysfunction in streptozotocin-induced diabetic rats, Reyna VanGilder

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The effect of C8-arylguanine adducts on B/Z-DNA equilibrium: Implications in aryl hydrazine carcinogenesis, Vorasit Vongsutilers

Theses/Dissertations from 2008

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Involvement of adenosine A1 receptors in systemic inflammation and altered vascular reactivity in allergic mice, Dovenia S. Ponnoth

Theses/Dissertations from 2007

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Effects of the common pesticide methoxychlor on ovarian steroidogenesis, Yucel Akgul

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Effect of diesel exhaust particles on allergic reactions and airway responsiveness in ovalbumin-sensitized brown Norway rats, Caroline Dong

Theses/Dissertations from 2006

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IQGAP1 knockdown enhances the endothelial barrier in vitro, Wentao Zhang

Theses/Dissertations from 2005

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Assessing the cost-effectiveness of tumor necrosis factor inhibitors and prescribing practices of rheumatologists in patients with rheumatoid arthritis, Khalid M. Kamal

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Pharmaceutical performance testing of commercially available calcium supplements, Jianqing Liu

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Economic evaluation of prophylactic antiemetic regimens for prevention of chemotherapy -induced nausea and vomiting (CINV), Reema R. Mody

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Quality of life and clinical outcomes in Type 2 diabetes patients at the primary care clinics of the West Virginia University Hospital, Murali Sundaram

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Mass spectrometry of metallothionein adducts as candidate biomarkers of styrene oxide and 1-phenylpropylene oxide, Sandra G. Tarr

Theses/Dissertations from 2004

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Characterization of CYP2D protein from human brain cerebellum, Deepak Bhatia

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Epidemiological burden of depression and its impact on adherence to oral hypoglycemic agents and related economic outcomes in patients with type 2 diabetes, Iftekhar D. Kalsekar

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Evaluation of novel cross -linking agents for gelatin/collagen matrices, Brenda J. Schuler

Theses/Dissertations from 2003

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Economics of breast cancer preventive strategies in a Medicaid program, Rohit D. Borker

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Evaluating utilization of beta -blockers as secondary prevention for post myocardial infarction in a Medicaid population, Ancilla W. Fernandes

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Dapsone activation of CYP2C9 allelic variants, Matthew Aaron Hummel

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Regulation of P-glycoprotein and ABCP transporters, Dhanashri Ramkrishna Kolwankar

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Uterine uptake of diazepam and quantification by gas chromatography/mass spectrometry, Steven Scott Wolfe

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Pharmaceutical quality performance of folic acid supplements, Islam Rasem Younis

Theses/Dissertations from 2002

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Triplex formation as monitored by EPR spectroscopy and molecular dynamics studies of spin -probe -labeled DNAs, Eva Darian

Theses/Dissertations from 2001

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Economic evaluation of three preventive drug therapies for osteoporotic fractures among women at different risk levels, Xin Gao

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Factors affecting CYP2C9-mediated metabolism, James Matthew Hutzler

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Transport and utilization of arginine and arginine-containing peptides by rat alveolar macrophages, Xiaodong Yang

Theses/Dissertations from 2000

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West Virginians' perceptions and use of complementary medicine, Joshua David Blevins

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IL -10 gene therapy for the treatment of pulmonary inflammation, Sujatha Dokka

Theses/Dissertations from 1999

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Evaluation of non-invasive biomarkers for carcinogenic exposure to cigarette smoke, Girish Srinivas Gudi